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由经过培训的眼科分级医师对先前成功治疗的糖尿病性黄斑水肿和增生性糖尿病性视网膜病变患者进行监测:来自 EMERALD 研究的成本分析。

Surveillance of people with previously successfully treated diabetic macular oedema and proliferative diabetic retinopathy by trained ophthalmic graders: cost analysis from the EMERALD study.

机构信息

Warwick Medical School, University of Warwick, Coventry, UK

Warwick Medical School, University of Warwick, Coventry, UK.

出版信息

Br J Ophthalmol. 2022 Nov;106(11):1549-1554. doi: 10.1136/bjophthalmol-2021-318816. Epub 2021 Jun 3.

Abstract

BACKGROUND/AIMS: Surveillance of people with previously successfully treated diabetic macular oedema (DMO) and proliferative diabetic retinopathy (PDR) adds pressure on ophthalmology services. This study evaluated a new surveillance pathway entailing multimodal imaging reviewed by trained ophthalmic graders and compared it with the current standard care (face-to-face evaluation by an ophthalmologist).

METHODS

Cost analysis of the new ophthalmic grader pathway, compared with the standard of care, from the perspective of the UK National Health Service, based on evidence from the Effectiveness of Multimodal imaging for the Evaluation of Retinal oedema And new vesseLs in Diabetic retinopathy study. Resource use data were prospectively obtained including times to undertake each procedure. Effectiveness was assessed in terms of sensitivity and specificity of referral decisions in the grader pathway. Costs (SDs) were analysed per 100 patients separately for DMO and PDR at 2018/2019 costs.

RESULTS

For DMO, where sensitivity was very high (97%), the cost difference (savings) for the grader's pathway would be £1390 per 100 patients. For PDR, the cost would be reduced by £461 for seven-field Early Treatment for Diabetic Retinopathy Study (ETDRS) images and by £1889 for ultrawide field images, per 100 patients. Ultrawide images required less time to be obtained and read than seven-field ETDRS. The real savings would be in ophthalmologist time, which could be then redirected to the evaluation of people at high risk of visual loss.

CONCLUSIONS

Surveillance of people with previously successfully treated DMO and PDR by trained ophthalmic graders can achieve satisfactory results and release ophthalmologist time.

TRIAL REGISTRATION NUMBERS

NCT03490318, ISRCTN10856638.

摘要

背景/目的:对先前成功治疗的糖尿病性黄斑水肿(DMO)和增生性糖尿病视网膜病变(PDR)患者进行监测会给眼科服务带来压力。本研究评估了一种新的监测途径,该途径涉及经过培训的眼科分级审查的多模态成像,并将其与当前的标准护理(由眼科医生进行面对面评估)进行了比较。

方法

从英国国家医疗服务体系的角度,根据 Effectiveness of Multimodal imaging for the Evaluation of Retinal oedema And new vesseLs in Diabetic retinopathy 研究中的证据,对新的眼科分级审查途径的成本与标准护理进行了成本分析。前瞻性地获得了资源使用数据,包括执行每个程序的时间。在分级审查途径中,通过转诊决策的敏感性和特异性来评估有效性。按 2018/2019 年的成本,分别分析了每 100 例 DMO 和 PDR 的成本(标准差)。

结果

对于 DMO,分级审查途径的敏感性非常高(97%),每 100 例患者的成本差异(节省)为 1390 英镑。对于 PDR,对于 7 字段早期糖尿病性视网膜病变治疗研究(ETDRS)图像,每 100 例患者的成本将减少 461 英镑,对于超广角图像,每 100 例患者的成本将减少 1889 英镑。超广角图像比 7 字段 ETDRS 图像需要更少的时间来获取和阅读。真正的节省将在眼科医生的时间上,这些时间可以重新用于评估那些有视力丧失高风险的人。

结论

经过培训的眼科分级审查可以对先前成功治疗的 DMO 和 PDR 患者进行监测,结果令人满意,并释放了眼科医生的时间。

临床试验注册号

NCT03490318,ISRCTN86011124。

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