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硝苯地平用于高位脊髓损伤男性电射精时可增加电流传输及精子采集量。

Increased current delivery and sperm collection using nifedipine during electroejaculation in men with high spinal cord injuries.

作者信息

VerVoort S M, Donovan W H, Dykstra D D, Syers P

机构信息

Department of Physical Medicine, Baylor College of Medicine, Houston, TX 77030.

出版信息

Arch Phys Med Rehabil. 1988 Aug;69(8):595-7.

PMID:3408330
Abstract

Elevated blood pressure associated with autonomic hyperreflexia during electroejaculation in persons with high spinal cord injuries often prevents successful sperm retrieval. The ability of the calcium channel blocker nifedipine to reduce the effects of autonomic hyperreflexia, to facilitate greater current delivery, and to increase sperm collection was evaluated in six persons with spinal cord injuries. Ten milligrams of nifedipine given sublingually ten to 15 minutes before electroejaculation attempts helped to moderate autonomic hyperreflexia and the associated blood pressure elevations. These effects of nifedipine allowed greater current delivery and ultimately increased the chances of successful sperm retrieval in the six men. No adverse drug effects were observed.

摘要

在高位脊髓损伤患者进行电射精时,与自主神经反射亢进相关的血压升高常常会阻碍精子的成功获取。对6名脊髓损伤患者评估了钙通道阻滞剂硝苯地平减轻自主神经反射亢进的影响、促进更大电流传输以及增加精子采集量的能力。在尝试电射精前10至15分钟舌下含服10毫克硝苯地平有助于减轻自主神经反射亢进及相关的血压升高。硝苯地平的这些作用使得能够传输更大电流,并最终增加了这6名男性成功获取精子的几率。未观察到药物不良反应。

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