[Location of enzymes of acetylcholine hydrolysis in smooth muscle cells of the breast and uterus].

The data on distribution of cholinesterase activity in smooth myocytes of the mammary ducts and in the tissue of normal and pathologically altered myometrium are presented. In the myometrium tumorous tissue, as demonstrate hystochemical investigation results, terminals of the nervous fibers are practically absent, while in the norm they are present in the intermuscular plexuses and accompany blood vessels. At the myomic alteration of the uterine smooth musculature, in myocytes a high enzymatic activity of the acetylcholine hydrolysis enzymes is revealed. An essentially activity of cholinesterases is found in the smooth myocytes of the mammary ducts. Participation of the acetylcholine hydrolysis and synthesis mechanisms in organization of rhythmic contractile activity is discussed.