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对乙酰氨基酚毒性所致暴发性肝肾综合征:一例报告

Fulminant hepatorenal syndrome due to Acetaminophen toxicity: A case report.

作者信息

Nekoukar Zahra, Moghimi Minoo, Zakariaei Zakaria, Fakhar Mahdi, Tabaripour Rabeeh

机构信息

Department of Clinical Pharmacy Faculty of Pharmacy Mazandaran University of Medical Sciences Sari Iran.

Toxoplasmosis Research Center Communicable Diseases Institute Iranian National Registry Center for Lophomoniasis and Toxoplasmosis Mazandaran University of Medical Sciences Sari Iran.

出版信息

Clin Case Rep. 2021 Mar 24;9(5):e04037. doi: 10.1002/ccr3.4037. eCollection 2021 May.

Abstract

HRS is a rare and poor prognosis complication of chronic acetaminophen toxicity, which presents by progressive decline in renal function secondary to liver failure.

摘要

肝肾综合征是慢性对乙酰氨基酚中毒的一种罕见且预后不良的并发症,其表现为继发于肝功能衰竭的肾功能进行性下降。

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本文引用的文献

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Dissecting the molecular pathophysiology of drug-induced liver injury.解析药物性肝损伤的分子病理生理学。
World J Gastroenterol. 2018 Apr 7;24(13):1373-1385. doi: 10.3748/wjg.v24.i13.1373.
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Hepatoprotective Effect of ψ-Glutathione in a Murine Model of Acetaminophen-Induced Liver Toxicity.
Chem Res Toxicol. 2017 Mar 20;30(3):777-784. doi: 10.1021/acs.chemrestox.6b00291. Epub 2017 Feb 16.
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Acetaminophen hepatotoxicity: an updated review.对乙酰氨基酚肝毒性:最新综述
Arch Toxicol. 2015 Feb;89(2):193-9. doi: 10.1007/s00204-014-1432-2. Epub 2014 Dec 24.

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