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多次血管内治疗后小脑脑桥裂动静脉畸形的显微外科治疗

Microsurgical treatment for cerebellomesencephalic fissure arteriovenous malformations after multiple sessions of endovascular treatment.

作者信息

Lessa Silvio Sarmento, Paz-Archilla Juan Alberto, Amorim Bruno Loof, Filho Jose Maria Campos, de Siqueira Campos Christiane Monteiro, de Deus Silva Leonardo, Choque Richard Gonzalo Parraga, da Costa Marcos Devanir Silva, Chaddad-Neto Feres

机构信息

Department of Neurosurgery, Universidade Federal de São Paulo, Brazil.

Department of Radiology, Hospital Beneficencia Portuguesa de São Paulo, Brazil.

出版信息

Surg Neurol Int. 2021 May 10;12:214. doi: 10.25259/SNI_187_2021. eCollection 2021.

DOI:10.25259/SNI_187_2021
PMID:34084641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8168656/
Abstract

BACKGROUND

Arteriovenous malformations (AVMs) are relatively uncommon congenital vascular anomalies, and only 7-15% of AVMs occur in the posterior fossa. Most posterior fossa AVMs clinically present with hemorrhage and are associated with a high risk of neurological deficits and mortality. These malformations are associated with a high incidence of flow-related aneurysms. Endovascular treatment of infratentorial AVMs is challenging in pediatric patients.

CASE DESCRIPTION

We describe an 11-year-old female adolescent with cerebellar syndrome [Video 1], who was diagnosed with a cerebellomesencephalic fissure AVM. We observed a sequential increase in the size of the AVM after multiple sessions of endovascular treatment and performed successful microsurgical resection of the lesion.

CONCLUSION

This illustrative video highlights the role of microsurgery as a feasible therapeutic strategy for complete resection of cerebellar AVMs after endovascular embolization.

摘要

背景

动静脉畸形(AVM)是相对罕见的先天性血管异常,仅7%-15%的AVM发生于后颅窝。大多数后颅窝AVM临床上表现为出血,且与神经功能缺损和死亡的高风险相关。这些畸形与血流相关动脉瘤的高发生率有关。小儿患者幕下AVM的血管内治疗具有挑战性。

病例描述

我们描述了一名患有小脑综合征的11岁女性青少年[视频1],她被诊断为小脑脑桥裂AVM。我们观察到在多次血管内治疗后AVM大小呈序贯性增加,并成功地对该病变进行了显微手术切除。

结论

这段演示视频突出了显微手术作为血管内栓塞后完全切除小脑AVM的一种可行治疗策略的作用。

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Microsurgical treatment for cerebellomesencephalic fissure arteriovenous malformations after multiple sessions of endovascular treatment.多次血管内治疗后小脑脑桥裂动静脉畸形的显微外科治疗
Surg Neurol Int. 2021 May 10;12:214. doi: 10.25259/SNI_187_2021. eCollection 2021.
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本文引用的文献

1
Posterior fossa brain arteriovenous malformations : Clinical features and outcomes of endovascular embolization, adjuvant microsurgery and radiosurgery.后颅窝脑动静脉畸形:血管内栓塞、辅助显微手术和放射外科治疗的临床特征及结果
Clin Neuroradiol. 2018 Mar;28(1):17-24. doi: 10.1007/s00062-016-0514-3. Epub 2016 May 6.
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Endovascular treatment of posterior fossa arteriovenous malformations.后颅窝动静脉畸形的血管内治疗
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Association between posterior fossa arteriovenous malformations and prenidal aneurysm rupture: potential impact on management.后颅窝动静脉畸形与产前动脉瘤破裂之间的关联:对治疗的潜在影响。
Neurosurg Focus. 2014 Sep;37(3):E4. doi: 10.3171/2014.6.FOCUS14219.
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Neurosurg Rev. 2014 Oct;37(4):619-28. doi: 10.1007/s10143-014-0551-9. Epub 2014 May 9.
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Interdisciplinary clinical management of high grade arteriovenous malformations and ruptured flow-related aneurysms in the posterior fossa.后颅窝高级别动静脉畸形和破裂的血流相关动脉瘤的多学科临床管理
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Endovascular treatment of pial AVMs: technical options, indications and limits in pediatric age patients.
J Neurosurg Sci. 1997 Dec;41(4):325-30.
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Arteriovenous malformations of the posterior fossa: clinical presentation, diagnostic evaluation and surgical treatment.后颅窝动静脉畸形:临床表现、诊断评估及外科治疗
Neurosurg Rev. 1986;9(4):287-96. doi: 10.1007/BF01743635.