人类θ1-珠蛋白基因的核苷酸序列。
Nucleotide sequence of the human theta 1-globin gene.
作者信息
Gonzalez-Redondo J M, Han I S, Gu Y C, Huisman T H
机构信息
Department of Cell and Molecular Biology, Medical College of Georgia, Augusta 30912-3331.
出版信息
Biochem Genet. 1988 Apr;26(3-4):207-11. doi: 10.1007/BF00561460.
PMID:3408475
Abstract
We have cloned and sequenced the human theta 1-globin gene. The nucleotide sequence and organization of the human theta 1 gene (exons, introns, promoter, and polyadenylation signals) are similar to those reported for the orangutan theta 1-globin gene. If these genes are functional, the sequences of their theta 1-globin chains would differ by only one amino acid residue (at position 137).
摘要
我们已经克隆并测序了人类θ1-珠蛋白基因。人类θ1基因的核苷酸序列及结构（外显子、内含子、启动子和聚腺苷酸化信号）与报道的猩猩θ1-珠蛋白基因相似。如果这些基因具有功能，它们的θ1-珠蛋白链序列仅在一个氨基酸残基（第137位）上存在差异。
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