Jabbarvand Mahmoud, Khodaparast Mehdi, Jamali Alireza, Ahmadzadeh Hooman, Bordbar Soodeh
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
J Curr Ophthalmol. 2021 Mar 26;33(1):23-30. doi: 10.4103/JOCO.JOCO_154_20. eCollection 2021 Jan-Mar.
To investigate the changes in the optical corneal densitometry as an objective method in assessing the corneal light back-scattering before and 1 year after the annular intracorneal inlay (AICI) implantation into the keratoconic corneas.
Changes in the optical corneal densitometry, visual acuity, refractive, and tomographical status were assessed before and 1 year after the AICI implantation into the corneas with different stages of keratoconus. Optical corneal densitometry was evaluated using the Pentacam-HR in 0-2, 2-6, 6-10, and 10-12 mm rings in the anterior 120 μ, central layers, posterior 60 μ and also the total value were measured for cornea in the Grey Scale Unit criterion.
Totally, 34 patients with keratoconus were studied; the uncorrected and best corrected visual acuity were increased after the surgery (0.98 ± 0.25 to 0.53 ± 0.30 logMAR, < 0.001 and 0.26 ± 0.18 to 0.19 ± 0.14, = 0.007 logMAR, respectively); the spherical equivalent was decreased from -4.45 ± 2.25 to - 2.06 ± 2.01 D ( = 0.004). AICI implantation led to an increase in the amount of optical corneal densitometry in 0-2 mm central, 2-6 mm central, 6-10 mm central, total central, 2-6 mm posterior, and 2-6 mm total rings (all, < 0.05); however, a decrease was observed in 0-2 mm anterior ring ( = 0.049). Results of statistical analysis showed that the total optical corneal densitometry, anterior total, and posterior total back-scattering did not change after the AICI implantation (all, > 0.05).
Our results revealed a significant improvement in the visual function, including refractive error and visual acuity following the AICI implantation. Changes in the optical corneal densitometry were different in distinct regions and layers however, the total amount did not change after the AICI implantation.
研究光学角膜密度测定法作为一种客观方法，在圆锥角膜中植入角膜内环（AICI）术前及术后1年评估角膜光背散射的变化情况。
对不同阶段圆锥角膜在植入AICI术前及术后1年评估光学角膜密度测定、视力、屈光及断层扫描状态的变化。使用Pentacam-HR在角膜前120μm、中央层、后60μm的0-2mm、2-6mm、6-10mm和10-12mm环中评估光学角膜密度测定，并按照灰度单位标准测量角膜的总值。
共研究了34例圆锥角膜患者；术后未矫正视力和最佳矫正视力均有所提高（分别从0.98±0.25提高到0.53±0.30 logMAR，P<0.001；从0.26±0.18提高到0.19±0.14，P = 0.007 logMAR）；等效球镜度从-4.45±2.25降低到-2.06±2.01 D（P = 0.004）。AICI植入导致0-2mm中央、2-6mm中央、6-10mm中央、中央总值、2-6mm后部和2-6mm总值环的光学角膜密度测定值增加（均P<0.05）；然而，在0-2mm前部环观察到降低（P = 0.049）。统计分析结果显示，AICI植入后光学角膜密度测定总值、前部总值和后部总值背散射均未改变（均P>0.05）。
我们的结果显示，AICI植入后视觉功能有显著改善，包括屈光不正和视力。光学角膜密度测定在不同区域和层的变化不同，然而，AICI植入后总量未改变。
