Mosborg D A, Crane R T, Tami T A, Parker G S
Department of Otolarygology-Head and Neck Surgery, Naval Hospital, Portsmouth, Va.
Arch Otolaryngol Head Neck Surg. 1988 Sep;114(9):1038-40. doi: 10.1001/archotol.1988.01860210104027.
Carcinomas arising in burn scars are uncommon. Of the several hundred cases reported in the world's literature, 30% have been described in the head and neck region. Acute burn scar carcinoma, which occurs within one to two years of injury, is rare, while the chronic type, with an average latency of 35 years from injury to diagnosis, is much more common. Two cases of burn scar carcinoma are presented. Treatment is based on the histologic cell type (usually squamous cell or basal cell), in addition to the clinical stage. Adjuvant radiation therapy can often improve the results obtained with surgical excision alone. Proper initial treatment of burns, with early use of skin grafts, might curb the development of these potentially serious tumors.
烧伤瘢痕癌并不常见。在世界文献报道的数百例病例中，30%发生于头颈部区域。急性烧伤瘢痕癌在损伤后1至2年内发生，较为罕见，而慢性型从损伤到诊断的平均潜伏期为35年，更为常见。本文介绍了两例烧伤瘢痕癌病例。治疗除依据临床分期外，还基于组织学细胞类型（通常为鳞状细胞或基底细胞）。辅助性放射治疗常常可以改善单纯手术切除的效果。对烧伤进行恰当的初始治疗并早期使用皮肤移植，可能会抑制这些潜在严重肿瘤的发生。
