心肌梗死后室性心律失常的时间进程及信号平均心电图：一项相关性前瞻性研究
Time course of ventricular arrhythmias and the signal averaged electrocardiogram in the post-infarction period: a prospective study of correlation.
作者信息
Turitto G, Caref E B, Macina G, Fontaine J M, Ursell S N, el-Sherif N
机构信息
State University of New York, Health Science Center, Brooklyn, New York.
出版信息
Br Heart J. 1988 Jul;60(1):17-22. doi: 10.1136/hrt.60.1.17.
The incidence and time course of complex ventricular arrhythmias and of the abnormal signal averaged electrocardiogram were studied prospectively in 90 patients in the first two months after acute myocardial infarction. Serial recordings of both 24 hour ambulatory and signal averaged electrocardiograms were obtained 0-5 days (phase 1), 6-30 days (phase 2), and 31-60 days (phase 3) after infarction. A total of 264 ambulatory electrocardiograms and 264 signal averaged electrocardiograms were available for analysis. Complex ventricular arrhythmias were seen in 31%, 17%, and 38% of patients during phases 1, 2, and 3 respectively, and abnormal signal averaged electrocardiogram in 13%, 24%, and 16%. The incidence of complex ventricular arrhythmias was not significantly different in patients with or without an abnormal signal averaged electrocardiogram in the entire study period nor in any of the three phases after infarction. During phase 2 when abnormal signal averaged electrocardiograms were most common complex ventricular arrhythmias were least common. This lack of correlation suggests that the abnormal signal averaged electrocardiogram and complex ventricular arrhythmias after infarction have different electrophysiological bases.
对90例急性心肌梗死后头两个月的患者进行前瞻性研究，观察复杂室性心律失常的发生率和病程以及异常信号平均心电图情况。在梗死后0 - 5天（阶段1）、6 - 30天（阶段2）和31 - 60天（阶段3）分别进行24小时动态心电图和信号平均心电图的系列记录。共有264份动态心电图和264份信号平均心电图可供分析。在阶段1、2和3中，分别有31%、17%和38%的患者出现复杂室性心律失常，异常信号平均心电图的出现率分别为13%、24%和16%。在整个研究期间以及梗死后三个阶段中的任何一个阶段，有或没有异常信号平均心电图的患者，其复杂室性心律失常的发生率均无显著差异。在阶段2，异常信号平均心电图最为常见，而复杂室性心律失常最为少见。这种缺乏相关性表明，梗死后异常信号平均心电图和复杂室性心律失常具有不同的电生理基础。
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