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因暴露于哥伦比亚波哥大农村家庭室内空气污染物而导致的肺量计参数变化。

Spirometry parameter alterations due to exposure to indoor air pollutants in rural homes in Bogotá, Colombia.

机构信息

Pós-graduação em saúde Coletiva. Bolsista CAPES, Universidade Estadual de Feira de Santana (UEFS), Feira de Santana, Brazil.

Faculty of Engineering, National University of Colombia, Bogotá, Colombia.

出版信息

Environ Sci Pollut Res Int. 2021 Oct;28(40):57275-57287. doi: 10.1007/s11356-021-14717-5. Epub 2021 Jun 4.

DOI:10.1007/s11356-021-14717-5
PMID:34086176
Abstract

The aim of this study was to determine the association between the concentrations of intradomiciliary PM, CO, and BC and alterations in respiratory function parameters in a population living in rural dwellings in Bogotá, Colombia. For this cross-sectional study, people were recruited from the rural areas of the localities of Usme and Sumapaz in Bogotá. In total, 68 participants were recruited by means of nonrandom sampling. Indoor air monitoring of PM, BC, and CO was carried out. Additionally, evaluations of pulmonary function were performed using spirometry. The variables of pulmonary function were included in a multiple linear regression by successive steps and adjusted by the main variables described as modifiers of spirometry parameters, which are age, height, sex, disability, and a history of tobacco use. Assumptions of multicollinearity and the randomization of variances in the residuals were evaluated. Negative associations were found between spirometry parameters and the concentrations of indoor air pollutants. For FEV1/FVC and theoretical FEV1, there was a statistically significant association with the concentration of carbon monoxide (p = 0.003 and 0.019, respectively). The environmental concentrations were higher in homes where biomass was used for cooking, but these differences were statistically significant only for BC and CO (p = 0.008 and 0.03, respectively). The concentrations of carbon monoxide in rural homes were associated with alterations in respiratory function parameters.

摘要

本研究旨在确定哥伦比亚波哥大农村居民室内空气中 PM、CO 和 BC 浓度与呼吸功能参数改变之间的关联。在这项横断面研究中,我们从波哥大的 Usme 和 Sumapaz 地区招募了农村居民。总共通过非随机抽样招募了 68 名参与者。我们对 PM、BC 和 CO 进行了室内空气监测。此外,还使用肺活量计进行了肺功能评估。通过逐步多元线性回归将肺功能变量纳入其中,并通过描述为肺活量计参数修正因子的主要变量进行了调整,这些变量包括年龄、身高、性别、残疾和吸烟史。我们评估了多共线性假设和残差的随机性。肺活量计参数与室内空气污染物浓度之间存在负相关。对于 FEV1/FVC 和理论 FEV1,与一氧化碳浓度存在统计学显著关联(p 值分别为 0.003 和 0.019)。在使用生物质燃料做饭的家庭中,环境浓度更高,但仅对于 BC 和 CO 而言,这些差异具有统计学意义(p 值分别为 0.008 和 0.03)。农村家庭中一氧化碳浓度与呼吸功能参数改变相关。

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