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Lateral Habenula Serves as a Potential Therapeutic Target for Neuropathic Pain.

作者信息

Du Yu, Wu Yu-Xing, Guo Fang, Qu Feng-Hui, Hu Ting-Ting, Tan Bei, Wang Yi, Hu Wei-Wei, Chen Zhong, Zhang Shi-Hong

机构信息

Department of Pharmacology and Department of Anesthesiology of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.

Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China.

出版信息

Neurosci Bull. 2021 Sep;37(9):1339-1344. doi: 10.1007/s12264-021-00728-2. Epub 2021 Jun 4.

DOI:10.1007/s12264-021-00728-2
PMID:34086264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8423943/
Abstract
摘要

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本文引用的文献

1
GAD2 Expression Defines a Class of Excitatory Lateral Habenula Neurons in Mice that Project to the Raphe and Pontine Tegmentum.GAD2 表达定义了一类在小鼠中兴奋性外侧缰核神经元，它们投射到中缝核和脑桥被盖。
eNeuro. 2020 May 20;7(3). doi: 10.1523/ENEURO.0527-19.2020. Print 2020 May/Jun.
2
Tacr3 in the lateral habenula differentially regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia.外侧缰核中的 Tacr3 差异调节三叉神经痛小鼠模型中的口腔触诱发痛和焦虑样行为。
Acta Neuropathol Commun. 2020 Apr 7;8(1):44. doi: 10.1186/s40478-020-00922-9.
3
Low-frequency Stimulation at the Subiculum is Anti-convulsant and Anti-drug-resistant in a Mouse Model of Lamotrigine-resistant Temporal Lobe Epilepsy.在拉莫三嗪耐药性颞叶癫痫小鼠模型中，海马下托的低频刺激具有抗惊厥和抗耐药性作用。
Neurosci Bull. 2020 Jun;36(6):654-658. doi: 10.1007/s12264-020-00482-x. Epub 2020 Mar 10.
4
Current and future directions of deep brain stimulation for neurological and psychiatric disorders.深部脑刺激治疗神经和精神疾病的现状和未来方向。
J Neurosurg. 2019 Aug 1;131(2):333-342. doi: 10.3171/2019.4.JNS181761.
5
The inhibitory effect of different patterns of low frequency stimulation on neuronal firing following epileptiform activity in rat hippocampal slices.不同模式的低频刺激对大鼠海马切片癫痫样活动后神经元放电的抑制作用。
Brain Res. 2019 Mar 1;1706:184-195. doi: 10.1016/j.brainres.2018.11.012. Epub 2018 Nov 9.
6
Deep brain stimulation for treatment-resistant depression: an integrative review of preclinical and clinical findings and translational implications.深部脑刺激治疗难治性抑郁症：临床前和临床研究结果及转化意义的综合综述。
Mol Psychiatry. 2018 May;23(5):1094-1112. doi: 10.1038/mp.2018.2. Epub 2018 Feb 27.
7
TLR4 deficiency abrogated widespread tactile allodynia, but not widespread thermal hyperalgesia and trigeminal neuropathic pain after partial infraorbital nerve transection.TLR4 缺陷消除了广泛的触诱发痛，但不能消除眶下神经部分切断后的广泛热痛觉过敏和三叉神经病理性疼痛。
Pain. 2018 Feb;159(2):273-283. doi: 10.1097/j.pain.0000000000001100.
8
The possible mechanisms of analgesia produced by microinjection of morphine into the lateral habenula in the acute model of trigeminal pain in rats.大鼠三叉神经痛急性模型中向外侧缰核微量注射吗啡产生镇痛作用的可能机制。
Res Pharm Sci. 2017 Jun;12(3):241-248. doi: 10.4103/1735-5362.207205.
9
The Role of Psychosocial Processes in the Development and Maintenance of Chronic Pain.心理社会过程在慢性疼痛的发生和维持中的作用。
J Pain. 2016 Sep;17(9 Suppl):T70-92. doi: 10.1016/j.jpain.2016.01.001.
10
Unmasking the mysteries of the habenula in pain and analgesia.揭开缰核对疼痛和镇痛的神秘面纱。
Prog Neurobiol. 2012 Feb;96(2):208-19. doi: 10.1016/j.pneurobio.2012.01.004. Epub 2012 Jan 14.