Department of Pathology, Hospital Clínico de Santiago de Compostela, Santiago, Spain.
Department of Forensic Sciences and Pathology, University of Santiago de Compostela, Santiago, Spain.
Am J Dermatopathol. 2021 Oct 1;43(10):732-735. doi: 10.1097/DAD.0000000000001773.
Angioleiomyomas are benign neoplasms, which usually present as solitary, slow-growing nodules on the skin of lower extremities, but acral location on the hands or feet is unusual. Yet, microscopically, they may show many histopathological variants, focal calcification is uncommon. Extensive calcification masquerading the real nature of the tumor has been rarely reported, the term acral calcified leiomyoma having been proposed for this entity. This change is more often in distal locations and has been interpreted as degenerative in nature, probably related to repetitive minor trauma. We report 3 examples of this unusual condition on the feet of 2 male and one female subjects (aged, 68, 69, and 80 years) and make a review of the 31 cases available in the literature. Two of our cases are associated with highly uncommon features, such as transepidermal calcium elimination and concomitant calcaneal spur.
血管平滑肌瘤是良性肿瘤，通常表现为下肢皮肤单发、生长缓慢的结节，但手足等肢端部位较为少见。然而，显微镜下，它们可能有许多组织病理学的变异型，局灶性钙化并不常见。广泛的钙化伪装肿瘤的真实性质的情况很少见，为此提出了肢端钙化平滑肌瘤这一术语。这种变化更多见于远端位置，被认为具有退行性，可能与反复的轻微创伤有关。我们报告了 3 例这种罕见情况，发生于 2 名男性和 1 名女性患者的足部（年龄分别为 68、69 和 80 岁），并对文献中 31 例可获得的病例进行了回顾。我们的 2 例病例与非常罕见的特征相关，如经皮钙消除和同时存在的跟骨骨刺。
