Department of Cardiology, Medline Adana Hospital, Adana, Turkey.
Department of Cardiology, Okmeydani Training and Research Hospital, Istanbul, Turkey.
Tex Heart Inst J. 2021 Jun 4;48(2). doi: 10.14503/THIJ-19-7092.
A high morning surge in systolic blood pressure poses a risk in people who have cardiovascular disease. We investigated the relationship between this phenomenon and the SYNTAX score I in patients who had stable coronary artery disease. Our single-center study included 125 consecutive patients (109 men and 16 women; mean age, 54.3 ± 9 yr) in whom coronary angiography revealed stable coronary artery disease. We calculated each patient's sleep-trough morning surge in systolic blood pressure, then calculated the SYNTAX score I. The morning surge was significantly higher in patients whose score was >22 (mean, 22.7 ± 13.2) than in those whose score was ≤22 (mean, 12.4 ± 7.5) (P <0.001). Forward stepwise logistic regression analysis revealed that morning surge in systolic blood pressure was the only independent predictor of an intermediate-to-high score (odds ratio=1.183; 95% CI, 1.025-1.364; P=0.021). To our knowledge, this is the first study to show an association between morning surge in systolic blood pressure and the SYNTAX score I in patients who have stable coronary artery disease.
清晨收缩压高峰在心血管疾病患者中存在风险。我们研究了这种现象与稳定型冠状动脉疾病患者的 SYNTAX 评分 I 之间的关系。我们的单中心研究纳入了 125 例连续患者（109 名男性和 16 名女性；平均年龄 54.3±9 岁），这些患者的冠状动脉造影显示存在稳定型冠状动脉疾病。我们计算了每位患者的睡眠中清晨收缩压高峰，然后计算了 SYNTAX 评分 I。评分 >22 的患者的清晨收缩压高峰显著高于评分≤22 的患者（平均值分别为 22.7±13.2 和 12.4±7.5，P<0.001）。向前逐步逻辑回归分析显示，清晨收缩压高峰是中高危评分的唯一独立预测因子（优势比=1.183；95%可信区间，1.025-1.364；P=0.021）。据我们所知，这是第一项表明稳定型冠状动脉疾病患者清晨收缩压高峰与 SYNTAX 评分 I 之间存在关联的研究。
