Department of Orthopaedic Surgery, Shanghai Key Laboratory of Orthopaedic Implants, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Department of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
J Surg Oncol. 2021 Sep;124(3):420-430. doi: 10.1002/jso.26516. Epub 2021 Jun 4.
The treatment of pelvic tumors is widely recognized to be challenging. The purpose of this study was to evaluate the efficacy of personalized three-dimensional (3D) printing-based limb salvage and reconstruction treatment for pelvic tumors.
Twenty-eight pelvic tumor patients were enrolled. 3D printing lesion models and osteotomy templates were prepared for surgery planning, prosthesis design, and osteotomy assistance during surgery. 3D printing-based personalized pelvic prostheses were manufactured and used in all 28 patients. Follow-up of postoperative survival, prosthesis survival, imaging examinations, and Musculoskeletal Tumor Society (MSTS) lower limb functional scores were carried out.
The mean follow-up period was 32.2 months, during which 16 patients had disease-free survival, 3 survived with the disease, and 9 died. The prostheses were stable, and the mean offset of the center of rotation was 5.48 mm. The prosthesis-bone interface showed good integration. For the 19 surviving patients, the mean MSTS lower limb functional score was 23.2. Postoperative complications included superficial infection in six patients and hip dislocation in three patients.
Personalized 3D printing-based limb salvage and reconstruction was an effective treatment for pelvic tumors. Our patients achieved good early postoperative efficacy and functional recovery.
骨盆肿瘤的治疗具有挑战性，这一观点已被广泛认可。本研究旨在评估基于个性化三维（3D）打印的保肢和重建治疗骨盆肿瘤的疗效。
纳入 28 例骨盆肿瘤患者。为手术规划、假体设计和手术中的截骨辅助制备了 3D 打印病变模型和截骨模板。对所有 28 例患者均采用基于 3D 打印的个性化骨盆假体进行治疗。对术后生存、假体生存、影像学检查和肌肉骨骼肿瘤学会（MSTS）下肢功能评分进行随访。
平均随访 32.2 个月，无瘤生存 16 例，带瘤生存 3 例，死亡 9 例。假体稳定，旋转中心平均偏移 5.48mm。假体-骨界面显示良好的融合。19 例存活患者的 MSTS 下肢功能评分平均为 23.2。术后并发症包括 6 例浅表感染和 3 例髋关节脱位。
基于个性化 3D 打印的保肢和重建是治疗骨盆肿瘤的有效方法。我们的患者术后早期疗效和功能恢复良好。
