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多物种口腔生物膜抗菌凝胶的筛选方法。

Method for screening antimicrobial gels against multi-species oral biofilms.

机构信息

University of Rennes 1, NUMECAN INSERM U1241, CIMIAD, F-35043 Rennes, France.

University of Rennes 1, NUMECAN INSERM U1241, CIMIAD, F-35043 Rennes, France; CHU Pontchaillou, Rennes, France.

出版信息

J Microbiol Methods. 2021 Aug;187:106253. doi: 10.1016/j.mimet.2021.106253. Epub 2021 Jun 1.

Abstract

We described a microtiter plate-based method that was effectively tailored for testing gel formulations against oral multispecies biofilms established on peg-lids. This method lifts the limitations imposed mainly by the anaerobic nature of the targeted bacterial species and the viscous properties of the targeted treatments.

摘要

我们描述了一种微孔板检测方法,该方法可以有效地针对 peg 盖上建立的口腔多物种生物膜测试凝胶配方。该方法克服了主要由目标细菌的厌氧性质和目标处理的粘性性质所带来的限制。

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