Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Hans Sachs Str. 6, D-35039 Marburg, Germany.
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Hans Sachs Str. 6, D-35039 Marburg, Germany.
Psychoneuroendocrinology. 2021 Sep;131:105279. doi: 10.1016/j.psyneuen.2021.105279. Epub 2021 May 20.
Children with attention deficit hyperactivity disorder (ADHD) require increased caregiver assistance and supervision, and their parents have shown high perceived parenting stress. Hence, physiological adjustment processes in the caregivers, involving the hypothalamic-pituitary-adrenal axis, seem plausible. We analyzed the association between maternal hair cortisol concentration (HCC) and symptoms of ADHD in preschool-aged children. 150 mothers of 4-5-year-old children participated in the study. To determine the HCC, the first scalp-near 3 cm hair segment was used. ADHD symptoms of the child were measured using teacher- and parent-report questionnaires and a clinical interview with the mother. When controlling for several putative confounders, teacher-reported ADHD symptoms were significantly positively associated with mothers' HCC. No associations of HCC with the mother-reported ADHD symptoms of the child emerged. It is possible that teacher-reported ADHD symptoms of the child reflect relevant ADHD symptoms more validly. As our study is the first on this issue, cross-validation is needed.
患有注意缺陷多动障碍（ADHD）的儿童需要增加照顾者的帮助和监督，其父母的育儿压力感知也较高。因此，照顾者的生理调节过程（涉及下丘脑-垂体-肾上腺轴）似乎是合理的。我们分析了母亲头发皮质醇浓度（HCC）与学龄前儿童 ADHD 症状之间的关系。150 名 4-5 岁儿童的母亲参与了这项研究。为了确定 HCC，使用了第一个头皮附近 3 厘米的头发段。使用教师和家长报告的问卷以及与母亲的临床访谈来测量儿童的 ADHD 症状。在控制了几个潜在的混杂因素后，教师报告的 ADHD 症状与母亲的 HCC 呈显著正相关。HCC 与母亲报告的儿童 ADHD 症状之间没有关联。儿童的教师报告的 ADHD 症状可能更能准确地反映出相关的 ADHD 症状。由于我们的研究是首次针对该问题开展的，因此需要进行交叉验证。
