State Key Laboratory of Cardiovascular Disease, Center of Internal Medicine, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Beilishi Rd, Xicheng District, Beijing, 100037, People's Republic of China.
State Key Laboratory of Cardiovascular Disease, Center of Surgery, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, People's Republic of China.
BMC Cardiovasc Disord. 2021 Jun 4;21(1):273. doi: 10.1186/s12872-021-02077-4.
Coronary artery-to-pulmonary artery fistula is a rare disorder characterized by abnormal vascular communication between the coronary artery and pulmonary artery. While most patients remain asymptomatic, some might exhibit symptoms of myocardial ischemia, congestive heart failure, or even sudden cardiac death if coronary aneurysm, thrombosis, infective carditis, or other congenital cardiac defects coexist. Case presentation We present a 66-year-old male complaining of angina pectoris with a history of hypertension and active smoking. He was diagnosed with a coronary aneurysm based on coronary computed tomography angiography. We subsequently identified a coronary artery-to-pulmonary artery fistula with giant aneurysmal dilation on coronary angiography. Ultimately we conducted surgery ligation and aneurysmorrhaphy. During surgery, we discovered newly formed thrombus within the aneurysmal cavity. Histological analysis of the aneurysmal wall supported the diagnosis of the congenital disorder. Our patient was successfully discharged and remained asymptomatic at two months of follow-up.
We presented a rare and complex combination of congenital coronary artery-to pulmonary artery fistula, giant coronary aneurysmal dilatation, and thrombosis through multi-modality evaluations.
冠状动脉-肺动脉瘘是一种罕见的疾病,其特征是冠状动脉和肺动脉之间存在异常的血管交通。虽然大多数患者无症状,但如果存在冠状动脉瘤、血栓形成、感染性心内膜炎或其他先天性心脏缺陷,一些患者可能会出现心肌缺血、充血性心力衰竭甚至心源性猝死的症状。
我们报告了一例 66 岁男性患者,因高血压和主动吸烟史而出现心绞痛。他根据冠状动脉计算机断层血管造影检查被诊断为冠状动脉瘤。随后我们在冠状动脉造影中发现了冠状动脉-肺动脉瘘,并伴有巨大的动脉瘤样扩张。最终我们进行了手术结扎和动脉瘤修复。在手术中,我们发现动脉瘤腔内有新形成的血栓。动脉瘤壁的组织学分析支持先天性疾病的诊断。我们的患者成功出院,在随访两个月时无症状。
我们通过多模态评估呈现了一种罕见且复杂的先天性冠状动脉-肺动脉瘘、巨大冠状动脉瘤样扩张和血栓形成的组合。