Faculty of Medicine, University of Nis, Blvd. dr Zorana Djindjica 81, 18000, Nis, Serbia.
Clinic for Anesthesia and Intensive Therapy, Clinical Centre Nis, Blvd. dr Zorana Djindjica 48, 18000, Nis, Serbia.
Ir J Med Sci. 2022 Jun;191(3):1305-1313. doi: 10.1007/s11845-021-02659-3. Epub 2021 Jun 5.
Obesity is one of the most common clinical conditions in the pediatric population with an increasing prevalence ranging from 20 to 30% worldwide. It is well known that during ambulatory anesthesia, obese children are more prone to develop perioperative respiratory adverse events (PRAEs) associated with obesity. To avoid or at least minimize these adverse effects, a thorough preoperative assessment should be undertaken as well as consideration of specific anesthetic approaches such as preoxygenation before induction of anesthesia and optimizing drug dosing. The use of short-acting opioid and nonopioid analgesics and the frequent implementation of regional anesthesia should also be included. Noninvasive airway management, protective mechanical ventilation, and complete reversion of neuromuscular blockade and awake extubation also proved to be beneficial in preventing PRAEs. During the postoperative period, continuous monitoring of oxygenation and ventilation is mandatory in obese children. In the current review, we sought to provide recommendations that might help to reduce the severity of perioperative respiratory adverse events in obese children, which could be of particular importance for reducing the rate of unplanned hospitalizations and ultimately improving the overall postoperative recovery.
肥胖是儿科人群中最常见的临床病症之一,全球范围内的患病率从 20%到 30%不等,呈上升趋势。众所周知,在门诊麻醉期间,肥胖儿童更容易发生与肥胖相关的围手术期呼吸不良事件(PRAE)。为了避免或至少最小化这些不良影响,应进行彻底的术前评估,并考虑特定的麻醉方法,如麻醉诱导前预充氧和优化药物剂量。还应包括使用短效阿片类药物和非阿片类镇痛药以及频繁实施区域麻醉。非侵入性气道管理、保护性机械通气以及神经肌肉阻滞的完全逆转和清醒拔管也被证明有助于预防 PRAE。在术后期间,肥胖儿童必须持续监测氧合和通气。在本次综述中,我们试图提供一些建议,这些建议可能有助于减轻肥胖儿童围手术期呼吸不良事件的严重程度,这对于降低计划外住院率并最终改善整体术后恢复可能尤为重要。