Department of General Surgery, Cleveland Clinic, Weston, Florida; The Bariatric and Metabolic Institute, Cleveland Clinic, Weston, Florida.
Department of General Surgery, Cleveland Clinic, Weston, Florida; The Bariatric and Metabolic Institute, Cleveland Clinic, Weston, Florida.
Surg Obes Relat Dis. 2021 Sep;17(9):1616-1620. doi: 10.1016/j.soard.2021.05.004. Epub 2021 May 15.
Obesity is a major risk factor for the development of metabolic syndrome, coronary artery disease, and heart failure (HF). Rapid weight loss following bariatric surgery can significantly improve outcomes for patients with these diseases.
To assess whether bariatric surgery improves ventricular ejection fraction in patients with obesity who have heart failure.
Private practice, United States.
We conducted a retrospective review of echocardiographic changes in systolic functions in patients with obesity that underwent bariatric surgery at our institution. Patients were divided into 2 groups, those (1) without known preoperative HF and (2) with preoperative HF. We compared the left ventricular ejection fraction (LVEF) before and after bariatric surgery in both groups. Common demographics and co-morbidities were also analyzed.
A total of 68 patients were included in the analysis: 49 patients in group 1 and 19 in group 2. In group 1, 59.2% (n = 29) of patients were female, versus 57.9% (n = 11) in group 2. The excess body mass index lost at 12 months was 52.06 ± 23.18% for group 1 versus 67.12 ± 19.27% for group 2 (P = .0001). Patients with heart failure showed a significant improvement in LVEF, from 38.79 ± 13.26% before to 48.47 ± 14.57% after bariatric surgery (P = .039). Systolic function in patients from group 1 showed no significant changes (59.90 ± 6.37 mmHg) before and (59.88 ± 7.85 mmHg) after surgery (P = .98).
Rapid weight loss after bariatric surgery is associated with a considerable increase in LVEF and a significant improvement of systolic function.
肥胖是代谢综合征、冠状动脉疾病和心力衰竭（HF）发展的主要危险因素。减重手术后的快速体重减轻可以显著改善这些疾病患者的预后。
评估肥胖合并心力衰竭患者行减重手术后是否改善心室射血分数。
美国私人诊所。
我们对我院行减重手术的肥胖患者的超声心动图收缩功能变化进行了回顾性分析。患者分为两组，一组（1）无术前已知 HF，另一组（2）术前有 HF。我们比较了两组患者减重手术前后的左心室射血分数（LVEF）。还分析了常见的人口统计学和合并症。
共纳入 68 例患者进行分析：第 1 组 49 例，第 2 组 19 例。第 1 组中，59.2%（n=29）为女性，第 2 组中 57.9%（n=11）为女性。第 1 组患者 12 个月时多余体重指数丢失 52.06±23.18%，第 2 组为 67.12±19.27%（P=0.0001）。心力衰竭患者 LVEF 显著改善，从术前的 38.79±13.26%提高到术后的 48.47±14.57%（P=0.039）。第 1 组患者的收缩功能术前为 59.90±6.37mmHg，术后为 59.88±7.85mmHg（P=0.98），无显著变化。
减重手术后快速减肥与 LVEF 显著增加和收缩功能显著改善有关。
Zotero 插件