Whyte R I, Kaplan D K, Sharpe D A, Muehrcke D D, Donnelly R J
Department of General Surgery, Massachusetts General Hospital, Harvard Medical School, Boston.
Cancer. 1988 Sep 1;62(5):1014-6. doi: 10.1002/1097-0142(19880901)62:5<1014::aid-cncr2820620529>3.0.co;2-1.
In a series of 560 pulmonary resections for bronchial carcinoma, unsuspected microscopic tumor was present at the bronchial resection margin in 26 patients (4.5%). Adjuvant chemotherapy or radiotherapy was given in two patients. In follow-up times ranging from 1 to 72 months (mean, 22 months), 58% of patients were alive and free of recurrent disease. Twelve patients underwent periodic surveillance bronchoscopy in an attempt to identify early local recurrence. Eighty-three percent of these patients were alive and disease-free in follow-up times from 4 to 72 months (mean, 29.7 months). Only one choscopies. It was concluded that microscopic residual resection-line tumor does not preclude prolonged survival and that no benefit from surveillance bronchoscopy could be demonstrated in this small patient sample.
在一系列560例支气管癌肺切除术中，26例患者（4.5%）的支气管切除边缘存在未被怀疑的微小肿瘤。2例患者接受了辅助化疗或放疗。随访时间为1至72个月（平均22个月），58%的患者存活且无疾病复发。12例患者接受了定期监测支气管镜检查，试图发现早期局部复发。这些患者中有83%在4至72个月（平均29.7个月）的随访期内存活且无疾病。仅进行了一次支气管镜检查。得出的结论是，微小的手术切缘残留肿瘤并不妨碍长期生存，并且在这个小样本患者中未显示出监测支气管镜检查的益处。
