Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Department of Surgery, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, Pakistan.
J Pak Med Assoc. 2021 May;71(5):1455-1457. doi: 10.47391/JPMA.705.
Hepatocellular carcinoma is the sixth common cancer diagnosed and fourth leading cause of cancer-related deaths worldwide. Its incidence is on rise due to increasing prevalence of chronic hepatitis C virus infection. Pakistan is ranked second in countries burdened by hepatitis C virus in the world. Management of hepatocellular carcinoma is complex as it develops on the back of liver cirrhosis, and the risk of mortality is an accumulation of both tumour-related factors as well as liver decompensation. A multidisciplinary tumour board is an ideal approach to improve the outcomes of hepatocellular carcinoma since this ensures assimilation of input from a diverse group of care-providers, including hepatobiliary and transplant surgeons, gastroenterologists, interventional radiologists, oncologists and palliative care specialists. A multidisciplinary tumour board provides tailored approach to individual cases in a timely fashion to avoid treatment delays and communication gaps to improve the overall outcomes.
肝细胞癌是全球第六大常见癌症,也是癌症相关死亡的第四大主要原因。由于慢性丙型肝炎病毒感染的流行率不断上升,其发病率也在上升。巴基斯坦是世界上受丙型肝炎病毒感染负担第二大的国家。由于肝细胞癌是在肝硬化的基础上发展起来的,而且死亡率是肿瘤相关因素和肝功能失代偿的累积,因此其治疗非常复杂。多学科肿瘤委员会是改善肝细胞癌治疗效果的理想方法,因为它确保了来自不同类型的医疗服务提供者的输入,包括肝胆外科医生、移植外科医生、胃肠病学家、介入放射学家、肿瘤学家和姑息治疗专家。多学科肿瘤委员会及时为每个病例提供量身定制的方法,以避免治疗延误和沟通差距,从而提高整体治疗效果。