Department of Urology, Menoufia University Hospitals, Shebeen el kom, Egypt.
Department of Urology, Nasser Institute for Research and Treatment, Cairo, Egypt.
World J Urol. 2021 Nov;39(11):4215-4219. doi: 10.1007/s00345-021-03752-z. Epub 2021 Jun 6.
Transurethral resection of the prostate (TURP) can achieve highly satisfying symptomatic and functional outcomes but the loss of antegrade ejaculation represents a major reason for the avoidance of surgical treatment to preserve normal ejaculation and paternity. We present a novel technique to duplicate both bladder neck sparing and supramontanal sparing with resection of apical tissues to improve voiding and antegrade ejaculation.
A prospective study done from June 2018 to June 2020 on 60 consecutive male patients with normal sexual activity diagnosed with benign prostatic enlargement. These patients were randomized into two groups; 30 patients in each group. Group 1 underwent bladder neck and supramontanal sparing ejaculatory preserving transurethral bipolar resection of prostate (ep-TUBRP) and Group 2 underwent classic transurethral bipolar resection of prostate (c-TUBRP). All patients were evaluated pre- and postoperatively (after 3 months) using IPSS, Qmax and by IIEF-5.
In both groups, there were significant improvements 3 months postoperative in Qmax [7.97 mL/s to 18.47 mL/s (group A) and 7.8 to 20.7 mL/s (group B)] and in micturition symptoms according to reductions in IPSS score [24 to 7.5 (group A) and 25 to 8.5 (group B)]. IIEF-5 score improved significantly from a mean of 12.9 to 18.6 (group A) and from 11.6 to 16.4 (group B). Antegrade ejaculation reported in 80% of patients in group A and 27% in group B which was significant (p < 0.001). Postoperative period did not reveal acute urinary retention, stress urinary incontinence, or serious adverse events.
On short-term results, bladder neck and supramontanal ejaculation preserving transurethral bipolar resection of the prostate is superior to classic TURP in preservation of forward ejaculation with comparable efficacy in micturition parameters.
经尿道前列腺切除术(TURP)可以实现令人满意的症状和功能结果,但逆行射精的丧失是避免手术治疗以保留正常射精和生育能力的主要原因。我们提出了一种新的技术,通过切除顶端组织来复制膀胱颈部保留和鞍上保留,以改善排尿和逆行射精。
一项前瞻性研究于 2018 年 6 月至 2020 年 6 月对 60 例有正常性行为的良性前列腺增生男性患者进行,这些患者被随机分为两组,每组 30 例。组 1 行膀胱颈部和鞍上保留射精保留性经尿道双极前列腺切除术(ep-TUBRP),组 2 行经典经尿道双极前列腺切除术(c-TUBRP)。所有患者均在术前和术后(术后 3 个月)进行 IPSS、Qmax 和 IIEF-5 评估。
两组患者术后 3 个月时 Qmax[7.97mL/s 至 18.47mL/s(组 A)和 7.8 至 20.7mL/s(组 B)]和排尿症状均显著改善(IPSS 评分从 24 分降至 7.5 分[组 A]和从 25 分降至 8.5 分[组 B])。IIEF-5 评分从平均 12.9 分提高到 18.6 分(组 A)和从 11.6 分提高到 16.4 分(组 B)。组 A 中 80%的患者报告有逆行射精,组 B 中仅有 27%的患者报告有逆行射精,差异有统计学意义(p<0.001)。术后期间未出现急性尿潴留、压力性尿失禁或严重不良事件。
在短期结果中,膀胱颈部和鞍上保留射精的经尿道双极前列腺切除术在保留向前射精方面优于经典 TURP,在排尿参数方面具有可比性。