Kow Chia Siang, Hasan Syed Shahzad, Wong Pei Se, Verma Rohit Kumar
School of Postgraduate Studies, International Medical University, Kuala Lumpur, Malaysia.
School of Pharmacy, Monash University Malaysia, Bandar Sunway, Petaling Jaya, Selangor, Malaysia.
Clin Exp Hypertens. 2021 Oct 3;43(7):633-641. doi: 10.1080/10641963.2021.1925683. Epub 2021 Jun 6.
The endemic of hypertension along with high prevalence of uncontrolled hypertension in Southeast Asia indicates an important role for high-quality clinical practice guidelines (CPGs) to optimize the management of hypertension. However, there was no reported quality appraisal of the CPGs for the management of hypertension in Southeast Asia. This study aimed to evaluate methodological quality across the CPGs for the management of hypertension in Southeast Asia with a validated quality appraisal tool. The CPGs for the management of hypertension in Southeast Asia were retrieved from the websites of the Ministry of Health or cardiovascular specialty societies of the individual countries of Southeast Asia. Two reviewers with academic backgrounds independently appraised the methodological quality of all the included CPGs using the Appraisal of Guideline ResEarch and Evaluation (AGREE II) instrument. Six CPGs were identified, each of them from Thailand, Malaysia, Indonesia, Brunei, Singapore, and Vietnam. The highest-scoring quality domain was 'clarity of presentation' (mean=78.7 ± 14.6%), whereas the lowest-scoring quality domains were 'applicability' and 'editorial independence' (mean=8.4 ± 6.0% and mean=8.3 ± 18.6%, respectively). Except for the CPG originated from Malaysia which was "recommended" for use in practice (standardized score for three domains was ≥50.0%), the remaining five CPGs were "weakly recommended" for use in practice (standardized score for one to two domains was ≥50%). More efforts are needed to improve the quality of the developed CPGs for the management of hypertension in Southeast Asia.
东南亚地区高血压的流行以及高血压控制不佳的高患病率表明，高质量的临床实践指南（CPG）在优化高血压管理方面起着重要作用。然而，尚无关于东南亚地区高血压管理CPG的质量评估报告。本研究旨在使用经过验证的质量评估工具，评估东南亚地区高血压管理CPG的方法学质量。从东南亚各国卫生部或心血管专业协会的网站上检索了东南亚地区高血压管理的CPG。两名具有学术背景的评审员使用指南研究与评价（AGREE II）工具独立评估了所有纳入CPG的方法学质量。共识别出6份CPG，分别来自泰国、马来西亚、印度尼西亚、文莱、新加坡和越南。得分最高的质量领域是“表述清晰性”（均值=78.7 ± 14.6%），而得分最低的质量领域是“适用性”和“编辑独立性”（均值分别为8.4 ± 6.0%和8.3 ± 18.6%）。除了源自马来西亚的CPG被“推荐”在实践中使用（三个领域的标准化得分≥50.0%）外，其余五份CPG被“弱推荐”在实践中使用（一至两个领域的标准化得分≥50%）。需要做出更多努力来提高东南亚地区已制定的高血压管理CPG的质量。
