Jan Ravees, Alahdal Ayman, Bithal Parmod Kumar
Department of Anesthesiology and Perioperative Medicine, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.
Anesth Essays Res. 2020 Jul-Sep;14(3):467-473. doi: 10.4103/aer.AER_89_20. Epub 2021 Mar 22.
Surgeries in prone position expose a patient to multitude of complications including laryngeal edema which may be related to the volume of fluid administered. Administering larger volumes of fluid intraoperatively may contribute to significant tissue edema, leading many anesthesiologists to practice a restrictive fluid infusion strategy. Although previous studies have compared fluid infusion strategies, changes in airway dimensions leading to airway edema have not been extensively investigated. Here, we compared two fluid infusion regimens in patients undergoing spine surgery in the prone position, and assessed their association with airway edema by means of the cuff leak test (CLT).
The aim of this study was to test the hypothesis whether a larger volume of crystalloid administration in spine surgeries performed in prone position would result in greater chances of airway edema, than would a restricted infusion policy, utilizing the CLT.
After ethical committee approval, thirty patients, aged 21-60 years, American Society of Anesthesiologists Status I or II, scheduled for elective spine surgery in the prone position, were selected. Group 1 (restrictive group) received 3 mL.kg .h , whereas Group 2 (permissive group) received 5 mL.kg .h of crystalloids plus urine output replacement. The airway edema was assessed by CLT which was performed soon after intubation (1) and before extubation (2). Cuff leak volume (CLV) was calculated from the difference in tidal volumes before ( ) and after cuff deflation ( ). Airway edema was evaluated by calculating the differences in the CLV at 1 and 2 (ΔCLV); the more the value of Δ CLV which means greater difference between these two points, the more the decrease in laryngeal lumen, signifying an increased risk of airway edema.
Decrease in laryngeal lumen was observed in patients who received permissive fluid regimen than that of the restrictive group, signifying more chances of airway edema in the former group. In addition, a poor correlation was found between the duration of anesthesia and development of airway edema in our study group.
Because surgeries in the prone position are at risk of airway edema, restrictive fluid regimen strategy should be preferred over the liberal one as there are more chances of reduction in laryngeal lumen dimensions with permissive fluid infusions.
俯卧位手术会使患者面临多种并发症,包括可能与液体输入量有关的喉水肿。术中输入大量液体可能导致明显的组织水肿,这使得许多麻醉医生采用限制性液体输注策略。尽管先前的研究比较了液体输注策略,但导致气道水肿的气道尺寸变化尚未得到广泛研究。在此,我们比较了俯卧位脊柱手术患者的两种液体输注方案,并通过套囊漏气试验(CLT)评估它们与气道水肿的关联。
本研究的目的是检验以下假设:在俯卧位脊柱手术中,与限制性输注策略相比,大量输注晶体液是否会导致气道水肿的几率更高,采用CLT进行验证。
经伦理委员会批准,选择30例年龄在21 - 60岁、美国麻醉医师协会分级为I或II级、计划行择期俯卧位脊柱手术的患者。第1组(限制性组)接受3 mL·kg·h的输注量,而第2组(允许性组)接受5 mL·kg·h的晶体液加尿量补充。通过在插管后不久(1)和拔管前(2)进行的CLT评估气道水肿。套囊漏气量(CLV)由套囊放气前后的潮气量差值计算得出。通过计算1和2时CLV的差值(ΔCLV)评估气道水肿;ΔCLV值越大,意味着这两个点之间的差异越大,喉腔减小越明显,表明气道水肿风险增加。
接受允许性液体输注方案的患者比限制性组患者的喉腔减小更明显,这表明前一组气道水肿的几率更高。此外,在我们的研究组中,麻醉持续时间与气道水肿的发生之间相关性较差。
由于俯卧位手术存在气道水肿风险,应优先选择限制性液体输注方案,因为允许性液体输注更有可能导致喉腔尺寸减小。