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仰卧位与俯卧位行经皮肾镜碎石术的比较:一项随机对照试验的荟萃分析。

Supine versus prone position for percutaneous nephrolithotripsy: A meta-analysis of randomized controlled trials.

机构信息

The Second Affiliated Hospital of Chongqing Medical University, Department of Urology, Chongqing, China.

出版信息

Int J Surg. 2019 Jun;66:62-71. doi: 10.1016/j.ijsu.2019.04.016. Epub 2019 Apr 26.

DOI:10.1016/j.ijsu.2019.04.016
PMID:31034987
Abstract

OBJECTIVE

To compare the safety and efficacy of percutaneous nephrolithotripsy (PCNL) in supine versus prone position for patients with renal or upper ureteral calculi.

METHODS

A systematic search of Pubmed, Embase and Cochrane Central Register of Controlled Trials was performed to identify all eligible studies. All included randomized controlled trials (RCTs) were evaluated based on the inclusion and exclusion criteria. After quality assessment and date extraction, a meta-analysis was performed using RevMan 5.3 software.

RESULTS

A total of 15 RCTs with 1474 patients were included in our meta-analysis. Pooled data showed that PCNL in supine position could significantly reduce the operative time [weighted mean difference (WMD) -12.02, 95% confidence interval (CI) -20.49 to -3.54, p = 0.005] and rate of fever [risk ratio (RR) 0.67, 95% CI 0.46 to 0.97, p = 0.03] compared to prone position. In addition, no significant differences could be found between groups in stone-free rate (p = 0.31), hospital stay (p = 0.59) and rate of overall complications (p = 0.11), mainly including urinary leakage (p = 0.83), pleural effusion (p = 0.74) and blood transfusion (p = 0.58).

CONCLUSIONS

The current study found comparable stone-free rate and significant lower rate of postoperative fever in supine PCNL compared with prone PCNL. PCNL in supine position could be a safe and efficient choice for patients with renal or upper ureteral calculi.

摘要

目的

比较肾结石或上段输尿管结石患者行俯卧位与仰卧位经皮肾镜碎石取石术(PCNL)的安全性和疗效。

方法

系统检索 Pubmed、Embase 和 Cochrane 中央对照试验注册库,以确定所有符合条件的研究。所有纳入的随机对照试验(RCT)均根据纳入和排除标准进行评估。在质量评估和数据提取后,使用 RevMan 5.3 软件进行荟萃分析。

结果

共纳入 15 项 RCT,共计 1474 例患者。汇总数据显示,仰卧位 PCNL 可显著缩短手术时间[加权均数差(WMD)-12.02,95%置信区间(CI)-20.49 至-3.54,p=0.005]和发热率[风险比(RR)0.67,95%CI 0.46 至 0.97,p=0.03],与俯卧位相比。此外,两组间结石清除率(p=0.31)、住院时间(p=0.59)和总体并发症发生率(p=0.11)无显著差异,主要包括尿漏(p=0.83)、胸腔积液(p=0.74)和输血(p=0.58)。

结论

本研究发现,与俯卧位 PCNL 相比,仰卧位 PCNL 结石清除率相似,但术后发热率显著降低。对于肾结石或上段输尿管结石患者,仰卧位 PCNL 是一种安全有效的选择。

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