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恢复期血浆作为印度尼西亚2019冠状病毒病的一种治疗方式：病例报告。

Convalescent plasma as a treatment modality for Coronavirus Disease 2019 in Indonesia: A case reports.

作者信息

Thabrani Achmad, Hadi Wahid Syamsul, Thobari Jarir At, Novianti Zakiah, Juliana Indah, Suharto Agus, Danaswari Atik Nuriyah, Septiani Ika, Rhatomy Sholahuddin

机构信息

Dr. Soeradji Tirtonegoro General Hospital, Klaten, Indonesia.

Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.

出版信息

Ann Med Surg (Lond). 2021 Jun;66:102444. doi: 10.1016/j.amsu.2021.102444. Epub 2021 May 31.

DOI:10.1016/j.amsu.2021.102444
PMID:34094533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8165043/
Abstract

INTRODUCTION AND IMPORTANCE

Coronavirus Disease 2019 (COVID-19) has become a pandemic since the beginning of 2020. COVID-19 is also spreading very rapidly in Indonesia and so far, no definitive therapy has been found.

CASE PRESENTATION

We report two cases of confirmed COVID-19 with moderate pneumonia, who received 400 ml of convalescent plasma and showed improvements in clinical, laboratory and radiological examinations.

CLINICAL DISCUSSION

Passive immunotherapy is generally more effective when given early. Plasma transfusion is more beneficial when given before clinical conditions become severe. Some studies have shown that therapy with convalescent plasma can contribute to a longer survival and a lower length of stay.

CONCLUSION

Convalescent plasma can be used as an adjunctive therapy option for patients with moderate COVID-19.

摘要

引言与重要性

自2020年初以来，2019冠状病毒病（COVID-19）已成为大流行病。COVID-19在印度尼西亚也传播得非常迅速，到目前为止，尚未找到确切的治疗方法。

病例报告

我们报告了两例确诊为COVID-19且患有中度肺炎的病例，他们接受了400毫升康复期血浆治疗，临床、实验室和影像学检查均显示有所改善。

临床讨论

被动免疫疗法通常在早期使用时效果更佳。在临床状况变得严重之前进行血浆输注更为有益。一些研究表明，康复期血浆治疗有助于延长生存期并缩短住院时间。

结论

康复期血浆可作为中度COVID-19患者的辅助治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e5/8187957/56bb1d1d87e2/gr8.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e5/8187957/56bb1d1d87e2/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e5/8187957/ecaf17748b0f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e5/8187957/7e21b8d51136/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e5/8187957/a50a2e2cfd0e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e5/8187957/1392b11a4f1a/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e5/8187957/811e604d793e/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e5/8187957/6985c454ab7b/gr6.jpg
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