Alli Ammar, Nabil Farah, Ortiz Juan Fernando
Internal Medicine, Tishreen University Faculty of Medicine, Latakia, SYR.
Internal Medicine, Universitat de Barcelona, Barcelona, ESP.
Cureus. 2021 May 1;13(5):e14790. doi: 10.7759/cureus.14790.
Despite the widespread Epstein-Barr virus (EBV) infections, we continue to see new reports with strange and unusual manifestations of the infection, which raises the question of how well we understand this pathogen. The age of contracting the infection is increasing in developed countries, which is changing the clinical presentation of those who get infected during their adolescence or early adulthood. In these stages, liver involvement is more prominent, and other physical symptoms are less apparent. Therefore, an update on infectious mononucleosis (IM) variable manifestation is required to make healthcare providers aware of this shift. This case stands as an example of the new shift as a patient scheduled for elective surgery suddenly presented with subclinical hepatitis caused by primary EBV infection. Our patient presented with few physical symptoms but had a classical picture of EBV-induced hepatitis on blood analysis. The diagnosis was missed by many physicians due to the varied presentations of IM. This case corresponds to the new evidence that suggests that hepatic involvement is one of the most prominent manifestation in the adult population with primary EBV infection.
尽管爱泼斯坦-巴尔病毒(EBV)感染广泛存在,但我们仍不断看到有关该感染奇怪和异常表现的新报告,这引发了我们对这种病原体了解程度的疑问。在发达国家,感染该病毒的年龄在增加,这正在改变那些在青春期或成年早期感染人群的临床表现。在这些阶段,肝脏受累更为突出,而其他身体症状则不太明显。因此,需要更新关于传染性单核细胞增多症(IM)可变表现的内容,以使医疗保健提供者了解这种转变。本病例就是这种新转变的一个例子,一名预定进行择期手术的患者突然出现由原发性EBV感染引起的亚临床肝炎。我们的患者身体症状较少,但血液分析显示有EBV诱导肝炎的典型表现。由于IM的表现多样,许多医生都漏诊了。该病例与新证据相符,即肝脏受累是原发性EBV感染成年人群中最突出的表现之一。