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一种专用的轻质钛化网片可预防开放性腹主动脉瘤(AAA)修复术后切口疝:一项初步前瞻性队列研究的结果。

A Dedicated Lightweight Titanized Mesh Prevents Incisional Hernias After Open Abdominal Aortic Aneurysm (AAA) Repair: Results of an Initial Prospective Cohort Study.

作者信息

Akingboye Akinfemi, Chaudhuri Arindam

机构信息

Colorectal Surgery, Russells Hall Hospital, Dudley, GBR.

Vascular Surgery, Bedfordshire-Milton Keynes Vascular Centre, Bedford, GBR.

出版信息

Cureus. 2021 May 3;13(5):e14821. doi: 10.7759/cureus.14821.

Abstract

Background Incisional hernia (IH) is a common, late complication of open repair of an abdominal aortic aneurysm (AAA), with a variable high incidence. A cohort study was conducted to investigate the role of a lightweight titanized mesh placed in the pre-peritoneal space after AAA repair. The primary endpoint was to determine the incidence of IH at eight weeks and 12 months. Methods Consecutive patients who underwent open repair of AAA with the prophylactic implantation of a mesh after abdominal wall closure were recruited. The development of IH was evaluated using clinical examination, ultrasonography scan (USS), and computed tomography (CT) scan during the follow-up period. Results Thirty-nine of 45 patients (34 male, 5 female, mean age 69.6 +/- 6.5 years) undergoing open repair of AAA over a five-year period via a preferred roof-top incision were analyzed for this study. One additional (2.5%) patient had the mesh explanted following a re-laparotomy for colonic ischemia and later developed an incisional hernia. There was no incidence of wound or mesh infection overall. One radiologically detected early IH closed spontaneously. There were five (12.8%) radiologically detected late cases of midline or paramedian defects beyond the one-year follow-up though this was not clinically significant; compared to this, there was no incidence of lateral defects in the wound (p<0.01, McNemar's test). Conclusion These preliminary results suggest that a dedicated lightweight titanized mesh is usable for primary reinforcement of rooftop incisions at the time of wound closure. Whilst this study supports the role of a mesh as a useful adjunct, larger studies and long-term follow-up would provide more sensitive assessments of its efficacy.

摘要

背景

切口疝(IH)是腹主动脉瘤(AAA)开放修复术后常见的晚期并发症,发病率不一且较高。进行了一项队列研究,以调查在AAA修复术后置于腹膜前间隙的轻质钛化补片的作用。主要终点是确定8周和12个月时IH的发生率。方法:招募在腹壁关闭后接受AAA开放修复并预防性植入补片的连续患者。在随访期间,通过临床检查、超声扫描(USS)和计算机断层扫描(CT)扫描评估IH的发生情况。结果:在五年期间,通过首选的屋顶切口对45例接受AAA开放修复的患者(34例男性,5例女性,平均年龄69.6±6.5岁)进行了分析。另有1例(2.5%)患者因结肠缺血再次剖腹手术后取出补片,随后发生切口疝。总体上没有伤口或补片感染的情况。1例经放射学检测到的早期IH自发闭合。在一年随访后,有5例(12.8%)经放射学检测到的中线或旁正中缺损晚期病例,尽管这在临床上不显著;相比之下,伤口外侧缺损没有发生率(p<0.01,McNemar检验)。结论:这些初步结果表明,一种专用的轻质钛化补片可用于伤口闭合时屋顶切口的初次加固。虽然这项研究支持补片作为一种有用辅助手段的作用,但更大规模的研究和长期随访将对其疗效提供更敏感的评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/044c/8171350/80982aa60f3a/cureus-0013-00000014821-i01.jpg

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