Bali C, Papakostas J, Georgiou G, Kouvelos G, Avgos S, Arnaoutoglou E, Papadopoulos G, Matsagkas M
Department of Surgery, Medical School, University of Ioannina, Ioannina, Greece.
Hernia. 2015 Apr;19(2):267-71. doi: 10.1007/s10029-014-1262-4. Epub 2014 May 13.
Open abdominal aortic aneurysm (AAA) repair is followed by a high rate of incisional herniation. The purpose of this study was to evaluate whether this postoperative complication could be avoided by a prophylactic implantation of a biological mesh.
In a prospective randomized clinical study, patients electively treated by open AAA repair were allocated equally to routine abdominal suture closure or to prophylactic placement of bovine pericardium mesh above the fascia. The study end points were postoperative complications and incidence of incisional hernia at a 3-year follow up.
Forty patients with a mean age of 74.3 (SD ± 5.8) years were studied. All patients had a successful operation and a quite uneventful postoperative course. The mean operative time in the mesh group was longer compared to the control group (p < 0.001). Two patients in the mesh group developed wound seroma postoperatively. Six patients (30%) in the control group developed incisional hernia comparing to none in the mesh group. Cumulative proportion of freedom from incisional hernia was 100% for mesh group at 3 years and 74.4% (SE 9.9%) for control group at 2 years (p < 0.008). In five patients (83%), the incisional hernia was diagnosed by the second postoperative year. One patient underwent incisional hernia repair.
The bovine pericardium mesh reinforcement of fascia closure in patients undergoing open AAA repair showed effectiveness and low complication rate in prophylaxis from incisional herniation. It should be considered as an alternative mesh material in selected patients.
开放性腹主动脉瘤(AAA)修复术后切口疝发生率很高。本研究的目的是评估通过预防性植入生物补片是否可以避免这种术后并发症。
在一项前瞻性随机临床研究中,接受开放性AAA修复术的患者被平均分为两组,一组采用常规腹部缝合关闭,另一组在筋膜上方预防性放置牛心包补片。研究终点为术后并发症以及3年随访时的切口疝发生率。
研究了40例平均年龄为74.3(标准差±5.8)岁的患者。所有患者手术均成功,术后过程平稳。补片组的平均手术时间比对照组更长(p < 0.001)。补片组有2例患者术后出现伤口血清肿。对照组有6例患者(30%)发生切口疝,而补片组无1例发生。补片组3年时无切口疝的累积比例为100%,对照组2年时为74.4%(标准误9.9%)(p < 0.008)。5例患者(83%)在术后第2年被诊断为切口疝。1例患者接受了切口疝修补术。
在接受开放性AAA修复术的患者中,使用牛心包补片加强筋膜关闭在预防切口疝方面显示出有效性且并发症发生率低。在特定患者中应将其视为一种替代补片材料。