利用“圣诞怪杰”追踪严重急性呼吸综合征冠状病毒2（SARS-CoV-2）谱系B.1.1.7和B.1.351/501Y-V2的国际传播情况
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch.
作者信息
O'Toole Áine, Hill Verity, Pybus Oliver G, Watts Alexander, Bogoch Issac I, Khan Kamran, Messina Jane P, Tegally Houriiyah, Lessells Richard R, Giandhari Jennifer, Pillay Sureshnee, Tumedi Kefentse Arnold, Nyepetsi Gape, Kebabonye Malebogo, Matsheka Maitshwarelo, Mine Madisa, Tokajian Sima, Hassan Hamad, Salloum Tamara, Merhi Georgi, Koweyes Jad, Geoghegan Jemma L, de Ligt Joep, Ren Xiaoyun, Storey Matthew, Freed Nikki E, Pattabiraman Chitra, Prasad Pramada, Desai Anita S, Vasanthapuram Ravi, Schulz Thomas F, Steinbrück Lars, Stadler Tanja, Parisi Antonio, Bianco Angelica, García de Viedma Darío, Buenestado-Serrano Sergio, Borges Vítor, Isidro Joana, Duarte Sílvia, Gomes João Paulo, Zuckerman Neta S, Mandelboim Michal, Mor Orna, Seemann Torsten, Arnott Alicia, Draper Jenny, Gall Mailie, Rawlinson William, Deveson Ira, Schlebusch Sanmarié, McMahon Jamie, Leong Lex, Lim Chuan Kok, Chironna Maria, Loconsole Daniela, Bal Antonin, Josset Laurence, Holmes Edward, St George Kirsten, Lasek-Nesselquist Erica, Sikkema Reina S, Oude Munnink Bas, Koopmans Marion, Brytting Mia, Sudha Rani V, Pavani S, Smura Teemu, Heim Albert, Kurkela Satu, Umair Massab, Salman Muhammad, Bartolini Barbara, Rueca Martina, Drosten Christian, Wolff Thorsten, Silander Olin, Eggink Dirk, Reusken Chantal, Vennema Harry, Park Aekyung, Carrington Christine, Sahadeo Nikita, Carr Michael, Gonzalez Gabo, de Oliveira Tulio, Faria Nuno, Rambaut Andrew, Kraemer Moritz U G
机构信息
Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
Department of Zoology, University of Oxford, Oxford, UK.
出版信息
Wellcome Open Res. 2021 Sep 17;6:121. doi: 10.12688/wellcomeopenres.16661.2. eCollection 2021.
Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website (cov-lineages.org/global_report.html) which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected.
2020年末，报告了两群具有生物学意义突变的严重急性呼吸综合征冠状病毒2（SARS-CoV-2），一群在英国，另一群在南非。我们结合常规监测、基因组测序和国际旅行数据，追踪了B.1.1.7和B.1.351谱系（501Y-V2变体）的国际传播情况。我们分别纳入了谱系首次报告地伦敦和南非的旅客数量，以考量基因组监测工作中的潜在偏差。使用软件工具grinch（全球新型冠状病毒单倍型调查报告），我们通过每日自动报告追踪相关谱系的国际传播情况。此外，我们建立了一个定制追踪网站（cov-lineages.org/global_report.html），该网站发布此每日报告，并将在检测到新的相关SARS-CoV-2谱系时持续纳入。
Zotero 插件