Lantz B, Selakovich W G, Collins D N, Garvin K L
Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock 72205.
Clin Orthop Relat Res. 1988 Sep(234):183-7.
A case of coccidioidomycosis of the knee caused by the fungus Coccidioides immitis demonstrates the chronicity of this disease as well as the disability incurred. The patient was completely asymptomatic for 11 years after initial treatment but developed progressive joint destruction, disabling pain, and loss of function. The nature of fungal infections in bone and joint necessitates long-term follow-up evaluation, even with adequate surgical debridement and medical therapy.
由粗球孢子菌引起的膝关节球孢子菌病病例显示了这种疾病的慢性病程以及由此导致的残疾。该患者在初始治疗后11年完全无症状,但随后出现了进行性关节破坏、致残性疼痛和功能丧失。骨与关节真菌感染的特性决定了即使进行了充分的手术清创和药物治疗,仍需要长期的随访评估。