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Monoclonal and oligoclonal anti-platelet factor 4 antibodies mediate VITT.单克隆和寡克隆抗血小板因子 4 抗体介导 VITT。
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Persistence of Ad26.COV2.S-associated vaccine-induced immune thrombotic thrombocytopenia (VITT) and specific detection of VITT antibodies.Ad26.COV2.S 相关疫苗诱导的免疫性血栓性血小板减少症（VITT）的持续存在和 VITT 抗体的特异性检测。
Am J Hematol. 2022 May;97(5):519-526. doi: 10.1002/ajh.26488. Epub 2022 Feb 21.

本文引用的文献

1
Vaccine-induced Immune Thrombocytopenia and Thrombosis (VITT).疫苗诱导的免疫性血小板减少症和血栓形成（VITT）
Res Pract Thromb Haemost. 2021 Jun 1;5(5):e12529. doi: 10.1002/rth2.12529. eCollection 2021 Jun.
2
Evaluation of laboratory assays for anti-platelet factor 4 antibodies after ChAdOx1 nCOV-19 vaccination.评价 ChAdOx1 nCOV-19 疫苗接种后抗血小板因子 4 抗体的实验室检测。
J Thromb Haemost. 2021 Aug;19(8):2007-2013. doi: 10.1111/jth.15362. Epub 2021 Jul 5.
3
US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021.美国 2021 年 3 月 2 日至 4 月 21 日 Ad26.COV2.S 疫苗接种后出现脑静脉窦血栓形成伴血小板减少的病例报告。
JAMA. 2021 Jun 22;325(24):2448-2456. doi: 10.1001/jama.2021.7517.
4
Updated Recommendations from the Advisory Committee on Immunization Practices for Use of the Janssen (Johnson & Johnson) COVID-19 Vaccine After Reports of Thrombosis with Thrombocytopenia Syndrome Among Vaccine Recipients - United States, April 2021.美国 2021 年 4 月：在报告接种强生（Johnson & Johnson）新冠疫苗的人群中出现血栓性血小板减少综合征后，免疫实践咨询委员会更新了强生疫苗的使用建议。
MMWR Morb Mortal Wkly Rep. 2021 Apr 30;70(17):651-656. doi: 10.15585/mmwr.mm7017e4.
5
Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination.接种 ChAdOx1 nCoV-19 疫苗后对血小板因子 4 的病理性抗体。
N Engl J Med. 2021 Jun 10;384(23):2202-2211. doi: 10.1056/NEJMoa2105385. Epub 2021 Apr 16.
6
SARS-CoV-2 Vaccine-Induced Immune Thrombotic Thrombocytopenia.严重急性呼吸综合征冠状病毒2型疫苗诱导的免疫性血栓性血小板减少症
N Engl J Med. 2021 Jun 10;384(23):2254-2256. doi: 10.1056/NEJMe2106315. Epub 2021 Apr 16.
7
Thrombotic Thrombocytopenia after Ad26.COV2.S Vaccination - Response from the Manufacturer.Ad26.COV2.S疫苗接种后血栓性血小板减少症——来自制造商的回应
N Engl J Med. 2021 May 20;384(20):1965-1966. doi: 10.1056/NEJMc2106075. Epub 2021 Apr 16.
8
Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination.接种 ChAdOx1 nCov-19 疫苗后发生血栓性血小板减少症。
N Engl J Med. 2021 Jun 3;384(22):2092-2101. doi: 10.1056/NEJMoa2104840. Epub 2021 Apr 9.
9
Diagnosis and Management of Vaccine-Related Thrombosis following AstraZeneca COVID-19 Vaccination: Guidance Statement from the GTH.接种阿斯利康 COVID-19 疫苗后的疫苗相关血栓形成的诊断和管理：GTH 的指导意见声明。
Hamostaseologie. 2021 Jun;41(3):184-189. doi: 10.1055/a-1469-7481. Epub 2021 Apr 1.

Vaccine-induced thrombotic thrombocytopenia following Ad26.COV2.S vaccine in a man presenting as acute venous thromboembolism.

作者信息

Abou-Ismail Mouhamed Yazan, Moser Karen A, Smock Kristi J, Lim Ming Y

机构信息

Division of Hematology and Hematologic Malignancies, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.

Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.

出版信息

Am J Hematol. 2021 Sep 1;96(9):E346-E349. doi: 10.1002/ajh.26265. Epub 2021 Jun 17.

DOI:10.1002/ajh.26265
PMID:34096082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8212083/
Abstract
摘要