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夏威夷 2012-2017 年妊娠期和产后人群重症监护病房入院的种族/民族差异。

Racial/Ethnic Disparities in Intensive Care Admissions in a Pregnant and Postpartum Population, Hawai'i, 2012-2017.

机构信息

3939 Department of Obstetrics, Gynecology, and Women's Health, University of Hawai'i John A. Burns School of Medicine, Honolulu, HI, USA.

Department of Quantitative Health Sciences, University of Hawai'i John A. Burns School of Medicine, Honolulu, HI, USA.

出版信息

Public Health Rep. 2022 Jul-Aug;137(4):711-720. doi: 10.1177/00333549211021146. Epub 2021 Jun 7.

DOI:10.1177/00333549211021146
PMID:34096822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9257516/
Abstract

OBJECTIVE

Maternal morbidity and mortality is a global concern despite advances in medical care and technology and improved economic resources of nations worldwide. The primary objective of our study was to describe racial/ethnic disparities in severe maternal morbidity by using admission to an intensive care unit (ICU) as a marker. The secondary objective was to evaluate associations between patient characteristics, including obstetric outcomes, and severe maternal morbidity.

METHODS

This retrospective cohort study used a large inpatient database to identify pregnancy and postpartum hospitalizations in Hawai'i from January 2012 through September 2017. We evaluated associations between sociodemographic and clinical characteristics and race/ethnicity by using χ tests. We used multivariable logistic regression to assess associations between race/ethnicity and ICU admission. We used a post hoc analysis to assess associations between ICU admission and obstetric outcomes by race/ethnicity.

RESULTS

After adjustment, we found a significantly higher ICU admission rate among Asian (adjusted odds ratio [aOR] = 1.30; 95% CI, 1.04-1.62; = .02), Filipino (aOR = 1.45; 95% CI, 1.17-1.79; < .001), and Native Hawaiian/Other Pacific Islander (aOR = 1.39; 95% CI, 1.15-1.68; < .001) women compared with non-Hispanic White women. Multiple clinical characteristics and outcomes were associated with ICU admission, such as preexisting chronic conditions and pregnancy-induced hypertensive disorders.

CONCLUSION

We found that severe maternal morbidity represented by ICU admission is higher among Asian, Filipino, and Native Hawaiian/Other Pacific Islander women than among non-Hispanic White women in Hawai'i. Our findings reemphasize the need for health care providers to be vigilant in caring for members of racial/ethnic minority groups and managing their comorbidities.

摘要

目的

尽管医疗保健和技术取得了进步,全球各国的经济资源也有所改善,但孕产妇发病率和死亡率仍然是一个全球性问题。我们研究的主要目的是使用入住重症监护病房(ICU)作为标志物来描述严重孕产妇发病率的种族/民族差异。次要目的是评估患者特征(包括产科结局)与严重孕产妇发病率之间的关联。

方法

本回顾性队列研究使用大型住院患者数据库,从 2012 年 1 月至 2017 年 9 月确定夏威夷的妊娠和产后住院情况。我们通过 χ2 检验评估社会人口学和临床特征与种族/民族之间的关联。我们使用多变量逻辑回归评估种族/民族与 ICU 入住之间的关联。我们进行了一项事后分析,以评估按种族/民族划分的 ICU 入住与产科结局之间的关联。

结果

调整后,我们发现亚洲人(调整后的优势比 [aOR] = 1.30;95%CI,1.04-1.62; =.02)、菲律宾人(aOR = 1.45;95%CI,1.17-1.79; <.001)和夏威夷原住民/其他太平洋岛民(aOR = 1.39;95%CI,1.15-1.68; <.001)的 ICU 入住率显著高于非西班牙裔白人女性。多种临床特征和结局与 ICU 入住相关,例如既往存在的慢性疾病和妊娠引起的高血压疾病。

结论

我们发现,在夏威夷,与非西班牙裔白人女性相比,亚洲人、菲律宾人和夏威夷原住民/其他太平洋岛民女性的 ICU 入住率更高,表明严重孕产妇发病率更高。我们的研究结果再次强调,医疗保健提供者需要保持警惕,为少数族裔群体成员提供护理并管理他们的合并症。