Department of Radiology, Northwell Health Lenox Hill Hospital, New York, NY.
Top Magn Reson Imaging. 2021 Jun 1;30(3):151-158. doi: 10.1097/RMR.0000000000000289.
Sinonasal tumors are relatively rare and radiographically challenging to evaluate due to their wide variety of pathologies and imaging features. However, sinonasal tumors possessing somatostatin receptor overexpression have the benefit of utilizing a multimodality anatomic and functional imaging for a more comprehensive evaluation. This is particularly evident with esthesioneuroblastoma, with computed tomography and magnetic resonance imaging defining the anatomic extent of the tumor, whereas somatostatin receptor imaging, particularly with gallium-68 DOTATATE positron emission tomography/computed tomography, is used to assess the presence of metastatic disease for staging purposes as well as in the surveillance for tumor recurrence. In addition, areas which accumulate gallium-68 DOTATATE are potentially amenable to treatment with peptide receptor radionuclide therapy. In this manner, a combined approach of anatomic and functional imaging is critical for optimal imaging evaluation and treatment strategy of patients with sinonasal tumors.
鼻腔鼻窦肿瘤相对少见，由于其病理和影像学表现广泛，因此放射学评估具有挑战性。然而，具有生长抑素受体过度表达的鼻腔鼻窦肿瘤受益于使用多种模态的解剖和功能影像学进行更全面的评估。这在嗅神经母细胞瘤中尤为明显，计算机断层扫描和磁共振成像定义了肿瘤的解剖范围，而生长抑素受体成像，特别是使用镓-68 DOTATATE 正电子发射断层扫描/计算机断层扫描，用于评估转移疾病的存在进行分期以及监测肿瘤复发。此外，积累镓-68 DOTATATE 的区域可能适合肽受体放射性核素治疗。通过这种方式，解剖和功能成像的综合方法对于鼻腔鼻窦肿瘤患者的最佳影像学评估和治疗策略至关重要。
