Biomedical Engineering and Technology Laboratory, Discipline of Mechanical Engineering, Indian Institute of Information Technology Design and Manufacturing, Jabalpur, MP, India.
Design and Vibrations Laboratory, Discipline of Mechanical Engineering, Indian Institute of Information Technology Design and Manufacturing, Jabalpur, MP, India.
Comput Methods Biomech Biomed Engin. 2021 Nov;24(15):1742-1751. doi: 10.1080/10255842.2021.1918123. Epub 2021 Jun 7.
The development of prosthetic bioimplants for fracture fixation using curved bone plates has been used as an established procedure for treatment in orthopedic. Here-in, we propose a novel curved bone plate fixation strategy to fix the designed biocompatible plates in different fracture models. Various biocompatible metallic biomaterials such as Ti-alloy (Ti-6Al-4V), stainless steel (SS 316L), and Co-alloy (Co-Cr) were created in SOLID works and used for the design of the bone plates. The typical fracture models (transverse and oblique) were created over a standard femur bone (models created using Materialize MIMIC/MAGIC) and two bone plates of similar materials were fixed side-by-side over the fractured femur using the screws made from Ti-6Al-4V. The finite element analysis (FEA) was carried out to evaluate the interface deformation, stress, and strain generated at the bone-bioimplant interface. The results from FEA demonstrated that the interface deformation and stress for a bone-bioimplant assembly are significantly reduced when natural anisotropic condition (functionally graded materials properties) of the human femur was well considered. Based on the analysis, Ti-6AL-4V and SS 316L were found as the best fit metallic biomaterials for the design and development of bone plate prosthetic bioimplants for fixation of an oblique fracture and transverse fracture respectively.
使用弯曲骨板进行骨折固定的假体生物植入物的开发已被用作矫形治疗的既定程序。在这里,我们提出了一种新的弯曲骨板固定策略,以将设计的生物相容性板固定在不同的骨折模型中。各种生物相容性金属生物材料,如钛合金(Ti-6Al-4V)、不锈钢(SS 316L)和钴合金(Co-Cr),均在 SOLID works 中创建,并用于骨板的设计。典型的骨折模型(横断和斜断)是在标准股骨(使用 Materialize MIMIC/MAGIC 创建的模型)上创建的,并用相同材料的两块骨板并排固定在断裂的股骨上,并用 Ti-6Al-4V 制成的螺钉固定。进行了有限元分析(FEA),以评估骨-生物植入物界面产生的界面变形、应力和应变。FEA 的结果表明,当充分考虑人体股骨的天然各向异性条件(功能梯度材料特性)时,骨-生物植入物组件的界面变形和应力显著降低。基于分析结果,Ti-6AL-4V 和 SS 316L 被发现是设计和开发用于固定斜骨折和横骨折的骨板假体生物植入物的最佳金属生物材料。