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[法国成年人哮喘患病率,来自康斯坦斯队列研究的数据]

[Prevalence of asthma among adults in France, data from the Constances cohort study].

作者信息

Delmas M-C, Bénézet L, Ribet C, Iwatsubo Y, Provost D, Varraso R, Zins M, Leynaert B, Nadif R, Roche N

机构信息

Santé publique France, 12, rue du Val d'Osne, 94415 Saint-Maurice cedex, France.

Santé publique France, 12, rue du Val d'Osne, 94415 Saint-Maurice cedex, France.

出版信息

Rev Mal Respir. 2021 Oct;38(8):797-806. doi: 10.1016/j.rmr.2021.05.007. Epub 2021 Jun 5.

DOI:10.1016/j.rmr.2021.05.007
PMID:34099358
Abstract

INTRODUCTION

The objectives of our study were to estimate the prevalence of asthma in adults in France and to study the effects of gender on the associations of asthma with the corpulence and socio-economic characteristics of individuals.

METHODS

We estimated the prevalence of current asthma (asthma attack in the past 12 months or current treatment for asthma) from data collected at inclusion in the Constances cohort study in 2013-2014. Analyses were performed separately in men and women, using robust Poisson regression for multivariate analysis.

RESULTS

Using data from 34,100 participants in the cohort (men: 47.7 %; mean age: 44.6 years), the prevalence of current asthma was estimated to be 5.8 % (5.1 % in men, 6.4 % in women). The risk of asthma was increased in women with high body mass index (BMI) or waist circumference. In men, only a high waist circumference was associated with an increased risk of asthma. An association with low socioeconomic status was observed only among women.

CONCLUSION

The associations of asthma with corpulence and socioeconomic status differed between men and women. Additional analyses should provide a better understanding of the mechanisms responsible for these differences.

摘要

引言

我们研究的目的是估计法国成年人哮喘的患病率,并研究性别对哮喘与个体肥胖及社会经济特征之间关联的影响。

方法

我们根据2013 - 2014年康斯坦茨队列研究纳入时收集的数据,估计当前哮喘(过去12个月内有哮喘发作或正在接受哮喘治疗)的患病率。在男性和女性中分别进行分析,使用稳健泊松回归进行多变量分析。

结果

利用该队列中34100名参与者的数据(男性占47.7%;平均年龄44.6岁),估计当前哮喘的患病率为5.8%(男性为5.1%,女性为6.4%)。体重指数(BMI)或腰围高的女性患哮喘的风险增加。在男性中,只有高腰围与哮喘风险增加相关。仅在女性中观察到与低社会经济地位的关联。

结论

哮喘与肥胖及社会经济地位之间的关联在男性和女性中存在差异。进一步的分析应能更好地理解造成这些差异的机制。

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