Franck H, Keck E, Issa S, Krüskemper H L, von Lilienfeld-Toal H
Department of Internal Medicine C, University of Düsseldorf, FRG.
Exp Clin Endocrinol. 1988 May;91(2):202-6. doi: 10.1055/s-0029-1210745.
Serum 1,25-dihydroxyvitamin D (1,25(OH)2D) is normal in some patients with chronic renal failure. We studied the question, whether factors known to regulate the serum 1,25(OH)2D concentration such as parathyroid hormone, calcium, phosphate and especially the serum 25 hydroxy vitamin D (25 OH D) concentration are related to circulating levels of serum 1,25(OH)2D in such patients. We found no correlation between these serum parameters and 1,25(OH)2D. Our data indicate that other factors are of more importance for the regulation of serum 1,25(OH)2D in this situation.
一些慢性肾衰竭患者的血清1,25 - 二羟维生素D（1,25(OH)₂D）水平正常。我们研究了如下问题，即已知调节血清1,25(OH)₂D浓度的因素，如甲状旁腺激素、钙、磷，尤其是血清25 - 羟维生素D（25 OH D）浓度，是否与这类患者血清1,25(OH)₂D的循环水平相关。我们发现这些血清参数与1,25(OH)₂D之间无相关性。我们的数据表明，在这种情况下，其他因素对血清1,25(OH)₂D的调节更为重要。
