Melling J, Hambleton P, Shone C C
Vaccine Research and Production Laboratory, Centre for Applied Microbiology and Research, Salisbury, Wiltshire.
Eye (Lond). 1988;2 ( Pt 1):16-23. doi: 10.1038/eye.1988.5.
C. botulinum neurotoxins are acutely toxic materials and act by inhibiting release of the neurotransmitter acetylcholine. The specific nature of this inhibition is discussed and the preparation and purification of Type A toxin specifically for clinical use is described.
肉毒杆菌神经毒素是剧毒物质，其作用机制是抑制神经递质乙酰胆碱的释放。本文讨论了这种抑制作用的具体性质，并描述了专门用于临床的A型毒素的制备和纯化方法。
