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不同年龄段患者接受软性输尿管镜手术的安全性和疗效。

Safety and Efficacy of Flexible Ureterorenoscopy Surgery in Different Age Groups.

机构信息

Department of Urology, Faculty of Medicine, Mustafa Kemal University, Antakya/Hatay, Turkey.

Department of Urology, HSU Izmir Bozyaka Training and Research Hospital, Izmir, Turkey.

出版信息

J Coll Physicians Surg Pak. 2021 Jun;31(6):679-685. doi: 10.29271/jcpsp.2021.06.679.

Abstract

OBJECTIVE

To comparatively investigate the efficacy, safety and complications of flexible ureterorenoscopy (f-URS) in the treatment of patients of different age groups (<60, 60-74 and ≥75 years) with proximal ureteral and kidney stones.

STUDY DESIGN

Descriptive study.

PLACE AND DURATION OF STUDY

Department of Urology, HSU Izmir Bozyaka Training and Research Hospital, HSU Ankara Diskapi Training, Research Hospital, and Mustafa Kemal University Faculty of Medicine, between March 2014 and June 2020.

METHODOLOGY

Nine hundred and fifty-six patients, who underwent f-URS due to proximal ureteral and kidney stones, were divided into three age groups as <60 years (Group 1), 60-74 years (Group 2) and ≥75 year (Group 3). The patients' American Society of Anesthesiologists (ASA) score, Charlson Comorbidity Index (CCI), anticoagulant use, stone-free rates and surgical and medical complication rates were examined for each group.

RESULTS

There were 688 patients in Group 1, 230 in Group 2, and 38 in Group 3. A significant difference was observed between the age groups in terms of CCI and anticoagulant use (p<0.001 for both). The highest rate of medical complications was observed in Group 3 at 42.1%, followed by Group 2 at 17.8%, while the lowest rate was observed in Group 1 at 2.3% (p<0.001). As a result of the multivariate analysis, receiving anticoagulant treatment (p=0.002) and having a high CCI (p=0.005) were independent predictors of medical complication development.

CONCLUSION

It was clearly demonstrated that f-URS could be used as a safe and effective alternative for the treatment of moderate-size kidney stones in all age groups. Key Words: Elderly, Geriatric patients, RIRS, Holmium laser lithotripsy, Urolithiasis, Safety, Efficacy.

摘要

目的

比较研究输尿管软镜(f-URS)治疗不同年龄组(<60 岁、60-74 岁和≥75 岁)肾盂输尿管上段结石患者的疗效、安全性和并发症。

研究设计

描述性研究。

研究地点和时间

2014 年 3 月至 2020 年 6 月在伊兹密尔博兹亚卡训练与研究医院泌尿科、安卡拉迪斯卡皮训练与研究医院泌尿科和玛特卡大学医学院进行。

方法

将 956 例因肾盂输尿管上段结石而行 f-URS 的患者分为<60 岁(第 1 组)、60-74 岁(第 2 组)和≥75 岁(第 3 组)3 个年龄组。检查每组患者的美国麻醉医师协会(ASA)评分、Charlson 合并症指数(CCI)、抗凝剂使用情况、结石清除率和手术及医疗并发症发生率。

结果

第 1 组 688 例,第 2 组 230 例,第 3 组 38 例。年龄组间 CCI 和抗凝剂使用情况存在显著差异(均 p<0.001)。第 3 组的医疗并发症发生率最高(42.1%),其次是第 2 组(17.8%),第 1 组最低(2.3%)(均 p<0.001)。多变量分析结果显示,抗凝治疗(p=0.002)和 CCI 较高(p=0.005)是发生医疗并发症的独立预测因素。

结论

f-URS 可作为所有年龄段治疗中等大小肾结石的安全有效替代方法。

关键词

老年人;老年患者;RIRS;钬激光碎石术;尿路结石;安全性;疗效。

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