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纳米技术在含有咖啡因的化妆品渗透方面的挑战。

Challenges of nanotechnology in cosmetic permeation with caffeine.

机构信息

Universidade Tecnológica Federal do Paraná, Programa de Pós-Graduação em Inovações Tecnológicas - PPGIT, Campo Mourão, PR, Brasil.

Universidade Tecnológica Federal do Paraná, Departamento de Engenharia de Alimentos, Campo Mourão, PR, Brasil.

出版信息

Braz J Biol. 2021 Jun 2;82:e241025. doi: 10.1590/1519-6984.241025. eCollection 2021.

DOI:10.1590/1519-6984.241025
PMID:34105652
Abstract

The evolution of beauty market and personal care is constant in Brazil as well in the rest of the world. Technological advances have brought up nanotechnology to the cosmetological field, employing active principles at atoms enveloped by vesicles, in order to take the active principle precisely to the target tissue to optimize the results achieved because of the considerable ease to cross skin barriers. Manufacturing of nanotechnology cosmetics is confronted with low absorption capacity. One of the many active principle found in cosmetic industry is caffeine, a pseudoalkaloid from the xanthine group used as a stimulant with the mechanism of the lipolytic action. This active is widely used in ​​a esthetics and cosmetics field in treatments involving dysfunctions such as localized fat and fibroedema geloid. To work out perfectly, the principle active need to interact and create a set of factors that includes lipolysis intensification. The caffeine encapsulation in gel-based nanocosmetics has the purpose of taking this active up to the adipocyte, the target cell, for mentioned dysfunctions treatment. Thus, we aim to present a review of how has been, the use of caffeine in the production of cosmetics.

摘要

巴西乃至全球的美容市场和个人护理产品都在不断发展。技术进步将纳米技术引入到化妆品领域,将活性成分封装在泡囊中,运用原子技术,以将活性成分精确地输送到目标组织,从而优化因皮肤屏障通透性显著提高而带来的效果。纳米技术化妆品的制造面临着低吸收率的问题。在化妆品行业中发现的众多有效成分之一是咖啡因,一种黄嘌呤组的拟生物碱,用作具有脂肪分解作用的兴奋剂。这种活性成分广泛用于治疗局部脂肪和纤维性水肿凝胶等功能障碍的美容和化妆品领域。为了达到最佳效果,有效成分需要相互作用并产生一系列因素,包括脂肪分解的增强。将咖啡因封装在基于凝胶的纳米化妆品中,目的是将这种活性成分输送到脂肪细胞,即目标细胞,以治疗上述功能障碍。因此,我们旨在介绍咖啡因在化妆品生产中的应用。

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