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[输血与妊娠对肾移植存活的有益作用]

[The beneficial role of blood transfusion and preganancy in the survival of renal allografts].

作者信息

Buy-Quang D, Soulillou J P, Fontenaille C, Guimbretière J, Guenel J

出版信息

Nouv Presse Med. 1977 Nov 12;6(38):3503-7.

PMID:341078
Abstract

This analysis involves 93 cases of transplants of non-related cadaver kidneys. The result was better (p = 0.02 at 1 year) in recipients transfused before the graft (73 cases) than in those who had not been trasfused (20 cases). However, this latter group had a shorter average period of haemodialysis (p = 0.05 than the first. The benefits of pre-immunisation appear from 1 to 2 transfusions or 1 pregnancy onwards (p = 0.02 at 1 year). Subjects transfused during the 6 months prior to the transplant had a graft which was functional more often than those who had been more than 6 months before the operation (p = 0.01 at 6 months). These results would be in favour of routine small quantity transfusions, approximately every six months in patients undergoing haemodialysis and on a waiting list for transplantation.

摘要

该分析涉及93例非亲属尸体肾移植病例。移植前输血的受者(73例)在1年时的结果比未输血的受者(20例)更好(p = 0.02)。然而,后一组的平均血液透析时间较短(比第一组p = 0.05)。免疫前的益处从1至2次输血或1次妊娠开始显现(1年时p = 0.02)。移植前6个月内输血的受试者的移植物功能正常的情况比手术前6个月以上输血的受试者更常见(6个月时p = 0.01)。这些结果支持常规小剂量输血,对于接受血液透析并在移植等待名单上的患者,大约每六个月输血一次。

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