左旋咪唑对犬体内成年犬恶丝虫的疗效有限。
Limited efficacy of levamisole against adults of Dirofilaria immitis in a dog.
作者信息
Barriga O O, Andujar F
机构信息
Department of Veterinary Pathobiology, Ohio State University, Columbus 43210-1092.
出版信息
J Am Vet Med Assoc. 1988 Jun 15;192(12):1743-4.
PMID:3410792
Abstract
A dog with chronic dirofilariasis (Dirofilaria immitis) was given 15 doses of 12 or 24 mg of levamisole/kg of body weight in 6 treatments within 96 days. Concentration of microfilariae in the blood was determined before and after treatment, and Aedes triseriatus mosquitoes were fed on the dog 1 to 5 days after each treatment and examined for D immitis larvae. Several adult worms were recovered from the dog 160 days after the end of the treatments.
摘要
一只患有慢性犬恶丝虫病（犬恶丝虫）的狗在96天内分6次接受了15剂，每千克体重12毫克或24毫克的左旋咪唑。在治疗前后测定血液中微丝蚴的浓度，在每次治疗后的1至5天，让三带喙库蚊叮咬这只狗，并检查是否有犬恶丝虫幼虫。在治疗结束160天后，从这只狗体内回收了几条成虫。
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