Otto von Guericke University of Magdeburg, Magdeburg, Germany.
University Clinic of Oral and Maxillofacial Surgery, Martin-Luther University, Halle-Wittenberg, Germany.
Head Face Med. 2021 Jun 9;17(1):19. doi: 10.1186/s13005-021-00270-6.
To develop and cross-validate site-specific panoramic radiography (PAN) analysis prediction equations of implant-to-mandibular canal dimensions (IMCD) in mandibular regions posterior to the mental foramen, and to help determine in which instances CBCT technology will be a justified adjunct in clinical practice.
IMCD by PAN (Pan-D) from implant site-specific regions (first premolar, second premolar, first molar, and second molar sites) were collected from 40- to 70-year-old adolescents. They were randomly assigned to validation (n = 144) and cross-validation (n = 148) groups. The cone-beam computed tomography (CBCT) technique was used as the criterion method for the estimation of IMCD (CBCT-D). The PAN analysis equations were developed using stepwise multiple regression analysis and cross-validated using the Bland-Altman approach.
There was a significant relationship between PAN-D and CBCT-D for both validation (R = 57.8 %; p < .001) and cross-validation groups (R = 52.5 %; p < .001). Root means-squared error (RMSE) and pure error (PE) were highest for the first molar (RMSE = 1.116 mm, PE = 1.01 mm) and the second molar region (RMSE = 1.162 mm, PE = 1.11 mm).
PAN-D has the potential to be developed as an indirect measure of IMCD. However, the findings suggest to exclude scoring of the first and second molars when assessing IMCD via PAN. Use of CBCT may be justified for all IMCD estimations in the first and second molars regions.
This study has been registered and approved by the Ethics Committee of the Martin-Luther University, Halle, Germany (2020-034).
开发并验证经口腔全景片（PAN）分析预测下颌后磨牙区种植体到下颌管（IMCD）的部位特异性预测方程，以帮助确定在哪些情况下 CBCT 技术将成为临床实践中的合理辅助手段。
从 40 至 70 岁青少年的种植体部位特异性区域（第一前磨牙、第二前磨牙、第一磨牙和第二磨牙部位）采集经 PAN 分析的 IMCD（Pan-D）。将其随机分配到验证组（n=144）和交叉验证组（n=148）。采用锥形束 CT（CBCT）技术作为 IMCD（CBCT-D）估计的标准方法。采用逐步多元回归分析方法建立 PAN 分析方程，并采用 Bland-Altman 方法进行交叉验证。
验证组（R=57.8%；p<0.001）和交叉验证组（R=52.5%；p<0.001）中，PAN-D 与 CBCT-D 之间均存在显著相关性。第一磨牙（RMSE=1.116 毫米，PE=1.01 毫米）和第二磨牙区（RMSE=1.162 毫米，PE=1.11 毫米）的均方根误差（RMSE）和纯误差（PE）最高。
PAN-D 有可能成为 IMCD 的间接测量指标。然而，研究结果表明，在通过 PAN 评估 IMCD 时，应排除对第一和第二磨牙进行评分。在第一和第二磨牙区，所有 IMCD 估计均可能需要使用 CBCT。
本研究已在德国马丁-路德-哈雷-维滕贝格大学伦理委员会（2020-034）注册并获得批准。
