与 1 型糖尿病作斗争。
Fighting the uphill battle to cure type 1 diabetes.
机构信息
Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Institute of Catholic Ubiquitous Health Care, The Catholic University of Korea, Seoul, Korea.
出版信息
J Diabetes Investig. 2021 Sep;12(9):1542-1544. doi: 10.1111/jdi.13613. Epub 2021 Jul 22.
Three complementary approaches for type 1 diabetes. Immunotherapy targets the pathogenic immune cells or inflammatory cytokines to revert type 1 diabetes. An artificial pancreas delivers insulin automatically using continuous glucose monitoring, a controlling algorithm, and an insulin pump. Beta cell replacement therapy varies depending on the cell sources: allogeneic, or xenogeneic islet; beta-like cells derived from ESCs or iPSCs.
三种治疗 1 型糖尿病的互补方法。免疫疗法针对致病免疫细胞或炎症细胞因子，以逆转 1 型糖尿病。人工胰腺使用连续血糖监测、控制算法和胰岛素泵自动输送胰岛素。β 细胞替代疗法因细胞来源而异：同种异体或异种胰岛；源自 ESCs 或 iPSCs 的β样细胞。
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