From the Departments of Clinical Investigation.
Pediatrics.
Sex Transm Dis. 2021 Aug 1;48(8):578-582. doi: 10.1097/OLQ.0000000000001393.
Mycoplasma genitalium is an important emerging sexually transmitted pathogen commonly causing urethritis in men, cervicitis, and pelvic inflammatory disease in women with potential of infertility. Accumulating evidence identifies the prevalence of M. genitalium similar to long recognized pathogens, Chlamydia trachomatis and Neisseria gonorrhoeae. The purpose of this study was to establish the prevalence and epidemiology of M. genitalium in a mid-Pacific military population.
A prospective analysis was conducted from routine specimens collected as standard of care for sexually transmitted infection (STI) testing at Tripler Army Medical Center on Oahu, HI. The prevalence of M. genitalium was determined using the Aptima M. genitalium assay, a transcription-mediated amplification test. A multivariate analysis was performed to assess the associations for this infection with other STIs and demographic factors.
A total of 1876 specimens were tested in a 6-month period including 6 sample types from 1158 females and 718 males. Subject ages ranged from 18 to 76 years, with a median of 24 years (interquartile range, 21-29 years). The prevalence of M. genitalium was 8.8% overall (n = 165), 7.1% in females and 11.6% in males. Coinfection with M. genitalium occurred with another sexually-transmitted pathogen in 43 patients (18.3%), with C. trachomatis as the most common organism (n = 38).
These data contribute to the evidence base for M. genitalium and STI screening in an active-duty military.
生殖支原体是一种重要的新兴性传播病原体，常引起男性尿道炎、女性宫颈炎和盆腔炎，并有潜在的不孕风险。越来越多的证据表明，生殖支原体的流行率与已被广泛认识的病原体沙眼衣原体和淋病奈瑟菌相似。本研究旨在确定中太平洋地区军事人群中生殖支原体的流行率和流行病学特征。
对夏威夷火奴鲁鲁的特里珀陆军医疗中心常规采集的标本进行前瞻性分析，这些标本是作为性传播感染（STI）检测标准护理的一部分。采用转录介导扩增检测（Aptima M. genitalium 检测）来确定生殖支原体的流行率。采用多变量分析来评估该感染与其他 STI 和人口统计学因素的关联。
在 6 个月的时间里，共检测了 1876 份标本，包括 1158 名女性和 718 名男性的 6 种样本类型。受试者年龄在 18 至 76 岁之间，中位数为 24 岁（四分位距 21-29 岁）。生殖支原体的总流行率为 8.8%（n = 165），女性为 7.1%，男性为 11.6%。43 名患者（18.3%）同时感染了生殖支原体和另一种性传播病原体，其中最常见的病原体是沙眼衣原体（n = 38）。
这些数据为现役军人生殖支原体和 STI 筛查提供了证据支持。
