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在 COVID-19 大流行相关的、州政府强制限制的情况下,紧急转入癫痫监测单元:临床决策和结果。

Emergent Admissions to the Epilepsy Monitoring Unit in the Setting of COVID-19 Pandemic-related, State-mandated Restrictions: Clinical Decision Making and Outcomes.

机构信息

Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas.

出版信息

Neurodiagn J. 2021 Jun;61(2):95-103. doi: 10.1080/21646821.2021.1918512. Epub 2021 Jun 10.

DOI:10.1080/21646821.2021.1918512
PMID:34110971
Abstract

Due to the coronavirus disease 2019 (COVID-19) pandemic, the state of Texas-limited elective procedures to conserve beds and personal protective equipment (PPE); therefore, between March 22 and May 18, 2020, admission to the epilepsy monitoring unit (EMU) was limited only to urgent and emergent cases. We evaluated clinical characteristics and outcomes of these patients who were admitted to the EMU. Nineteen patients were admitted (one patient twice) with average age of 36.26 years (11 female) and average length of stay 3 days (range: 2-9 days). At least one event was captured on continuous EEG (cEEG) and video monitoring in all 20 admissions (atypical in one). One patient had both epileptic (ES) and psychogenic non-epileptic seizures (PNES) while 10 had PNES and 9 had ES. In 8 of 9 patients with ES, medications were changed, while in 5 patients with PNES, anti-epileptic drugs (AED) were stopped; the remaining 5 were not on medications. Of the 14 patients who had seen an epileptologist pre-admission, 13 (or 93%) had their diagnosis confirmed by EMU stay; a statistically significant finding. While typically an elective admission, in the setting of the COVID-19 pandemic, urgent and emergent EMU admissions were required for increased seizure or event frequency. In the vast majority of patients (13 of 19), admission lead to medication changes to either better control seizures or to change therapeutics as appropriate when PNES was identified.

摘要

由于 2019 年冠状病毒病(COVID-19)大流行,德克萨斯州限制了择期手术以节省床位和个人防护设备(PPE);因此,2020 年 3 月 22 日至 5 月 18 日期间,癫痫监测病房(EMU)仅限制收治紧急和紧急情况的患者。我们评估了这些被收入 EMU 的患者的临床特征和结局。19 名患者(一名患者两次)被收入(其中一名患者两次),平均年龄 36.26 岁(11 名女性),平均住院时间 3 天(范围:2-9 天)。在所有 20 例入院中,至少有一次事件在连续脑电图(cEEG)和视频监测中被捕捉(一次为异常)。一名患者既有癫痫(ES)又有非癫痫性精神障碍(PNES),而 10 名患者有 PNES,9 名患者有 ES。在 9 名 ES 患者中有 8 名患者改变了药物治疗,而在 5 名 PNES 患者中有 5 名患者停止了抗癫痫药物(AED)治疗;其余 5 名患者未服用药物。在入院前见过癫痫专家的 14 名患者中,有 13 名(或 93%)通过 EMU 住院得到了确诊;这是一个具有统计学意义的发现。虽然通常是择期入院,但在 COVID-19 大流行期间,需要紧急和紧急 EMU 入院以增加癫痫发作或事件频率。在绝大多数患者(19 例中的 13 例)中,入院导致药物治疗改变,要么更好地控制癫痫发作,要么在识别出 PNES 时适当改变治疗方法。

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