高流量鼻氧管治疗与标准氧面罩治疗卧床肺炎患者的比较。
Comparison of high-flow nasal oxygen cannula therapy versus a standard oxygen face mask in patients with hypostatic pneumonia.
机构信息
Department of Respiratory and Critical Care Medicine, Harrison International Peace Hospital Affiliated to Hebei Medical University, Hengshui, China.
出版信息
J Int Med Res. 2021 Jun;49(6):3000605211022279. doi: 10.1177/03000605211022279.
OBJECTIVE
We assessed the clinical effects of high-flow nasal cannula (HFNC) oxygen therapy and a standard oxygen atomizer mask on the respiratory tract in patients with hypostatic pneumonia.
METHODS
We included patients with hypostatic pneumonia in this retrospective cohort study. Patients were provided continuous airway humidification by continuous oxygen atomization using either an HFNC or standard oxygen mask. Arterial blood gas analysis, the dyspnea score, inflammatory-related parameters, and adverse events of patients in the two groups were compared.
RESULTS
Fifty-five patients had HFNC delivery and 57 had a standard oxygen atomizer mask. After 7 days of treatment, patients in the HFNC group had a higher partial pressure of arterial blood oxygen/fraction of inspired oxygen ratio (268.12±28.44 vs 238.28±30.04) and lower partial pressure of arterial blood carbon dioxide (38.02±8.84 vs 49.27±7.84 mmHg) than those in the standard oxygen mask group. The dyspnea score and inflammatory-related parameters in the HFNC group were significantly lower than those in the standard oxygen mask group. The incidence of adverse events was lower in the HFNC group than in the standard oxygen mask group.
CONCLUSION
HFNC therapy relieves clinical symptoms more quickly than a standard oxygen mask and reduces the incidence of adverse events.
目的
评估高流量鼻导管（HFNC）氧疗与标准氧气雾化面罩对坠积性肺炎患者呼吸道的临床效果。
方法
本回顾性队列研究纳入坠积性肺炎患者。患者分别接受 HFNC 或标准氧气面罩持续气道湿化及持续氧雾化。比较两组患者的动脉血气分析、呼吸困难评分、炎症相关参数及不良事件。
结果
55 例患者接受 HFNC 治疗，57 例患者使用标准氧气雾化面罩。治疗 7 天后，HFNC 组患者的动脉血氧分压/吸入氧分数比值（268.12±28.44 比 238.28±30.04）更高，动脉血二氧化碳分压（38.02±8.84 比 49.27±7.84mmHg）更低；HFNC 组呼吸困难评分和炎症相关参数明显低于标准氧气雾化面罩组。HFNC 组不良事件发生率低于标准氧气雾化面罩组。
结论
HFNC 治疗比标准氧气面罩更能迅速缓解临床症状，降低不良事件发生率。
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