Soon Shereen X Y, Patel Ankur, Chong Tze Tec, Yap Charyl J Q, Tay Hsien Ts'ung, Tay Kiang Hiong, Sivanathan Chandramohan, Tang Tjun Y
Department of Vascular Surgery, Singapore General Hospital, Singapore.
Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore.
Vasc Specialist Int. 2021 Jun 11;37:13. doi: 10.5758/vsi.210016.
This study aimed to examine the distribution of lower limb atherosclerotic lesions in a multi-ethnic Asian cohort with chronic limb threatening ischemia (CLTI) from Singapore. The Society for Vascular Surgery Vascular Quality Initiative registry database was used to identify 265 CLTI patients who underwent percutaneous angioplasty between June 2019 and December 2019, of whom 171 (64.5%) were male, and the mean age was 67.9±11.0 years. The majority were diabetic (84.5%) and 145 (54.7%) had chronic kidney disease (CKD). The majority of the lower limb atherosclerotic lesions were de novo lesions (598/797, 75.0%), predominantly TransAtlantic Inter-Society Consensus II C/D (451/797, 56.6%), and were moderately to severely calcified (76.3%). The anterior tibial artery and femoral-popliteal artery were the most commonly affected vessels. The mean length of the treated lesions was 14.5±13.7 cm. There was a tendency, albeit insignificant, of multi-level disease in those who were diabetic or had CKD.
本研究旨在调查来自新加坡的患有慢性肢体威胁性缺血（CLTI）的多民族亚洲队列中下肢动脉粥样硬化病变的分布情况。利用血管外科学会血管质量改进注册数据库，确定了2019年6月至2019年12月期间接受经皮血管成形术的265例CLTI患者，其中171例（64.5%）为男性，平均年龄为67.9±11.0岁。大多数患者患有糖尿病（84.5%），145例（54.7%）患有慢性肾脏病（CKD）。大多数下肢动脉粥样硬化病变为新发病变（598/797，75.0%），主要为跨大西洋两岸社会共识II C/D级（451/797，56.6%），且有中度至重度钙化（76.3%）。胫前动脉和股腘动脉是最常受累的血管。治疗病变的平均长度为14.5±13.7厘米。糖尿病患者或患有CKD的患者存在多节段病变的趋势，尽管不显著。
