2019冠状病毒病疑似住院患者鼻咽检测阴性后严重急性呼吸综合征冠状病毒2下呼吸道检测的阳性率
Yield of Severe Acute Respiratory Syndrome Coronavirus 2 Lower Respiratory Tract Testing After a Negative Nasopharyngeal Test Among Hospitalized Persons Under Investigation for Coronavirus Disease 2019.
作者信息
Egbuonu Kenechukwu, Hyle Emily P, Hurtado Rocio M, Alba George A, Zachary Kimon C, Branda John A, Hibbert Kathryn A, Hooper David C, Shenoy Erica S, Turbett Sarah E, Dugdale Caitlin M
机构信息
Massachusetts Institute of Technology, Boston, Massachusetts, USA.
Medical Practice Evaluation Center, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
出版信息
Open Forum Infect Dis. 2021 May 19;8(6):ofab257. doi: 10.1093/ofid/ofab257. eCollection 2021 Jun.
Abstract
Among hospitalized persons under investigation for coronavirus disease 2019 (COVID-19), more repeated severe acute respiratory syndrome coronavirus 2 nucleic acid amplification tests (NAATs) after a negative NAAT were positive from lower than from upper respiratory tract specimens (1.9% vs 1.0%, = .033). Lower respiratory testing should be prioritized among patients displaying respiratory symptoms with moderate-to-high suspicion for COVID-19 after 1 negative upper respiratory NAAT.
摘要
在因2019冠状病毒病（COVID-19）接受调查的住院患者中，核酸扩增检测（NAAT）结果为阴性后，下呼吸道标本的严重急性呼吸综合征冠状病毒2重复NAAT检测呈阳性的比例高于上呼吸道标本（1.9%对1.0%，P = 0.033）。对于上呼吸道NAAT检测结果为阴性但高度怀疑COVID-19且有呼吸道症状的患者，应优先进行下呼吸道检测。
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