From the Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia.
Departments of Urology.
Clin Nucl Med. 2022 Jan 1;47(1):e101-e102. doi: 10.1097/RLU.0000000000003759.
A 65-year-old man with treated prostate adenocarcinoma underwent 68Ga-PSMA-11 PET/CT scan for restaging due to significantly increased serum PSA levels. PET/CT showed bilateral adrenal masses with high 68Ga-PSMA-11 uptake. There was no other lesion suspicious for metastasis. The laboratory and imaging findings were consisted with isolated bilateral adrenal metastases from prostate adenocarcinoma. The patient received docetaxel chemotherapy in combination with androgen deprivation therapy. PSA levels gradually decreased during chemotherapy. Follow-up MRI showed the bilateral adrenal masses significantly decreased in size. This case demonstrates the usefulness of 68Ga-PSMA-11 PET/CT in identifying atypical metastasis from prostate adenocarcinoma.
一位 65 岁患有前列腺腺癌的男性患者，由于血清 PSA 水平显著升高，进行了 68Ga-PSMA-11 PET/CT 扫描进行分期。PET/CT 显示双侧肾上腺肿块，摄取了高浓度的 68Ga-PSMA-11。没有其他疑似转移的病变。实验室和影像学检查结果与前列腺腺癌的孤立性双侧肾上腺转移相符。患者接受了多西他赛化疗联合雄激素剥夺治疗。化疗期间 PSA 水平逐渐下降。随访 MRI 显示双侧肾上腺肿块大小明显缩小。该病例证明了 68Ga-PSMA-11 PET/CT 在识别前列腺腺癌非典型转移中的作用。
